Search for dissertations about: "mevalonate"

Showing result 11 - 15 of 29 swedish dissertations containing the word mevalonate.

  2. 11. Protein Prenylation in Higher Eukaryotes

    Author : Ingela Parmryd; Patrick J Casey; Stockholms universitet; []
    Keywords : NATURVETENSKAP; NATURAL SCIENCES; biokemi; Biochemistry;

    Abstract : Protein prenylation is a post-translational process where proteins become covalently modified by an isoprenoid group. This modification adds hydrophobicity to the proteins. For all prenylated proteins identified to date, the prenyl group is an absolute requirement for their biological functions. READ MORE

  4. 12. Signaling mechanisms in Streptococcal M1 proteininduced inflammation and injury in the lung

    Author : Songen Zhang; Kirurgi; []
    Keywords : MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES;

    Abstract : Streptococcus pyogenes of the M1 serotype is frequently associated with severe streptococcal infections. Acute lung injury is recognized as a key component in the pathophysiology of streptococcal M1 proteininduced inflammation. READ MORE

  5. 13. Novel Agonists and Antagonists of Platelet Receptors

    Author : Carl Högberg; Kardiologi; []
    Keywords : MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; Platelets; P2Y12; SUCNR1; FPP; hypothermia;

    Abstract : Platelets are central for the primary haemostatis. The platelet has surface bound receptors that are vital for the platelet activation. READ MORE

  6. 14. Body constitution, statin use, and tumor characteristics. Implications for prognosis

    Author : Helga Tryggvadottir; Epidemiologi och farmakogenetik; []
    Keywords : MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; breast cancer; prognosis; tumor-specific markers; HMG-CoA reductase; aryl hydrocarbon receptor; aromatase; statins; anthropometric factors;

    Abstract : Breast cancer is an important cause of disease-burden and death in women. To prevent over- and undertreatment of breast cancer patients, new prognostic and predictive factors are needed. READ MORE

  7. 15. Role of dolichyl phosphate, N-linked glycosylation and cell membrane expression of insulin-like growth factor-1 receptor in maintenance of malignant cell growth

    Author : Anica Dricu; Karolinska Institutet; Karolinska Institutet; []
    Keywords : ;

    Abstract : Several studies have demonstrated that mevalonate (MVA) synthesis is required for cell proliferation. The mechanisms underlying MVA-regulated cell growth are still not fully understood. One conceivable mechanism for MVA-dependent cell growth is N-linked glycosylation of growth regulatory proteins. READ MORE