Search for dissertations about: "mice immunization"

Showing result 1 - 5 of 130 swedish dissertations containing the words mice immunization.

  2. 1. Novel immunization strategies and interethnic differences in response to malaria infection

    Author : Charles Arama; Marita Troye-Blomberg; Kai Matuschewski; Stockholms universitet; []
    Keywords : NATURVETENSKAP; NATURAL SCIENCES; Malaria; Immunization; Ethnic groups; vaccines; immunologi; Immunology;

    Abstract : A better understanding of the role of antigen-presenting cells (APCs) in host resistance to malaria is essential to unravel the complex interactions between the host and the parasite. This would improve the design of malaria vaccines. READ MORE

  4. 2. Studies in DNA immunization

    Author : Cecilia Svanholm; Karolinska Institutet; Karolinska Institutet; []
    Keywords : Chlamydia pneumoniae; DNA vaccine; GM-CSF; HIV-1; hsp60; Nef; Rev; Tat; signal sequence;

    Abstract : This thesis describes investigations and developments of DNA immunization techniques, which were applied in the study of two different pathogens; HIV-1 and Chlamydia pneumoniae. DNA vaccines, i.e. naked plasmid DNA encoding an antigen, represent a novel strategy for generating protective immunity against several infectious diseases. READ MORE

  5. 3. Development of a Cancer Vaccine Targeting Tumor Blood Vessels

    Author : Elisabeth J. M Huijbers; Anna-Karin Olsson; Arjan W. Griffioen; Uppsala universitet; []
    Keywords : MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; Vaccine; Therapeutic; Cancer; Tumor; Angiogenesis; Immunization; Vascular; Extracellular matrix; Biomedicinsk laboratorievetenskap; Biomedical Laboratory Science; Medical Cell Biology; Medicinsk cellbiologi; Oncology; Onkologi; Medical Science; Medicinsk vetenskap;

    Abstract : A treatment strategy for cancer is the suppression of tumor growth by directing an immune response to the tumor vessels, which will destroy the tissue.In this thesis we describe the development of a vaccine that targets antigens expressed around angiogenic vasculature in most solid tumors. READ MORE

  6. 4. Arthritis Susceptibility and Tolerance in Collagen Transgenic Mice

    Author : Vivianne Malmström; Immunologi; []
    Keywords : MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; rheumatology locomotion; animal model arthritis collagen autoimmunity tolerance cartilage mice; muscle system; Skeleton; Skelett; muskelsystem; reumatologi;

    Abstract : This thesis is based on work trying to understand the normal and pathological interactions taking place between the immune system and cartilage, specifically involving the cartilage-specific protein typ II collagen (CII). The work has been carried out in an experimental model of rheumatoid arthritis namely collagen type II induced arthritis (CIA) in mice. READ MORE

  7. 5. Prime-boost immunization strategies against HIV-1

    Author : Andreas Bråve; Karolinska Institutet; Karolinska Institutet; []
    Keywords : ;

    Abstract : Since the start of the global HIV epidemic in 1981, more than twentyfive million people have succumbed to AIDS-related diseases. The epidemic is most severe in Sub-Saharan Africa, where twentyfive million people are currently infected and more than two million died during 2006. READ MORE