Search for dissertations about: "mice lacking"

Showing result 1 - 5 of 284 swedish dissertations containing the words mice lacking.

  2. 1. Host-bacterium relationship in staphylococcal skin infection

    Author : Lena Mölne; Göteborgs universitet; []
    Keywords : MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; Staphylococcus aureus; skin; mice; superantigen; TSST-1; neutrophils; gamma delta T cells; bacterial DNA; CpG ODN;

    Abstract : Skin infections caused by Staphylococcus aureus are commonly occuring, both in the community and in hospitals. Despite the high prevalence of this condition, little is known about the host immune responsiveness and bacterial virulence factors during S. aureus skin infection. READ MORE

  4. 2. Coxsackie B virus pathogenesis in mice

    Author : Maria Hindersson; Karolinska Institutet; Karolinska Institutet; []
    Keywords : ;

    Abstract : Coxsackie B virus (CVB) belongs to the enterovirus (EV) genera of the Picornaviridae family. These infections range from asymptomatic, mild infections to serious diseases such as myocarditis, pancreatitis, paralysis, aseptic meningitis and encephalitis. READ MORE

  5. 3. Oscillatory Ca2+ signaling in glucose-stimulated murine pancreatic β-cells : Modulation by amino acids, glucagon, caffeine and ryanodine

    Author : Meftun Ahmed; Per Lindström; Uppsala universitet; []
    Keywords : MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; Cell biology; pancreatic β-cells; islets of Langerhans; glucose; Ca2 oscillations; Ca2 transients; potassium; ryanodine; caffeine; glucagon; cAMP; inositol 1; 4; 5-trisphosphate; fura-2; glycine; alanine; arginine; Ca2 channels; rats; lean mice; ob ob mice; leptin; Cellbiologi; Cell biology; Cellbiologi; medicinsk cellbiologi; Medical Cell Biology;

    Abstract : Oscillations in cytoplasmic Ca2+ concentration ([Ca2+]i) is the key signal in glucose-stimulated β-cells governing pulsatile insulin release. The glucose response of mouse β-cells is often manifested as slow oscillations and rapid transients of [Ca2+] i. READ MORE

  6. 4. Heparan Sulfate Biosynthesis – Clues from Knockout Mice

    Author : Johan Ledin; Lena Kjellén; John Gallagher; Uppsala universitet; []
    Keywords : NATURVETENSKAP; NATURAL SCIENCES; Cell and molecular biology; heparan sulfate; biosynthesis; gene targeting; embryonic development; proteoglycans; NDST; N-deacetylase N-sulfotransferase; Cell- och molekylärbiologi; Cell and molecular biology; Cell- och molekylärbiologi;

    Abstract : In the extracellular space, many specialized proteins are located to support cells and to mediate cell-cell signalling. One class of such molecules is heparan sulfate (HS) proteoglycans, which are proteins with different properties and locations but all of them decorated with long unbranched HS polysaccharide chains. READ MORE

  7. 5. Life without mitochondrial DNA : studies of transgenic mice

    Author : Jianming Wang; Karolinska Institutet; Karolinska Institutet; []
    Keywords : mitochondrial disease; mitochondrial DNA mtDNA ; mitochondrial transcripton factor A Tfam ; cre-loxP; conditional knockout; transgenic; mitochondrial cardiomyopathy; apoptosis;

    Abstract : Mitochondrial DNA (mtDNA) is a closed circular DNA genome that resides in the mitochondrial network. Mutations of mtDNA cause spontaneous and hereditary disorders known as mitochondrial diseases. Mitochondrial transcription factor A (Tfam) is a key factor for transcription of mtDNA in vitro. READ MORE