Search for dissertations about: "micro RNA"

Showing result 21 - 25 of 40 swedish dissertations containing the words micro RNA.

  2. 21. Molecular Palaeopathology : Ancient DNA analyses of the bacterial diseases tuberculosis and leprosy

    Author : Emilia Nuorala; Kerstin Lidén; Ingrid Ekenman; Marie Allen; Stockholms universitet; []
    Keywords : HUMANIORA; HUMANITIES; molecular palaeopathology; ancient DNA; disease; bacteria; tuberculosis; leprosy; Archaeology subjects; Arkeologiämnen;

    Abstract : This thesis “Molecular Palaeopathology. Ancient DNA analyses of the bacterial diseases tuberculosis and leprosy” deals with molecular palaeopathology, i.e. in this case the use of molecular methods to analyse ancient bacterial DNA in order to get further knowledge of diseases in ancient times. READ MORE

  4. 22. Microglia in the juvenile brain after cranial irradiation

    Author : Kai Zhou; Karolinska Institutet; Karolinska Institutet; []
    Keywords : ;

    Abstract : Radiotherapy is used to treat pediatric brain tumors and is often accompanied with debilitating late effects, such as cognitive decline. However, the mechanisms are poorly understood, and consequently there is still no effective treatment. READ MORE

  5. 23. Functional and Transcriptional Studies of Human Dopaminergic Neurons

    Author : Marcella Birtele; Utvecklings- och regenerativ neurobiologi; []
    Keywords : MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; Dopaminergic Neurons; Cell reprogramming; Cell therapy; Induced neurons; In vitro reprogramming; In vivo reprogramming;

    Abstract : Parkinson’s Disease (PD) is the most common movement disorder and second most common neurodegenerative disease. The principal hallmark of the pathology is represented by a loss of mesencephalic Dopaminergic neurons (mesDA) that reside in the Substantia Nigra pars compacta (SNpc). READ MORE

  6. 24. Molecular markers for prediction of response and progression free survival to novel therapies in cutaneous malignant melanoma

    Author : Fernanda Costa Svedman; Karolinska Institutet; Karolinska Institutet; []
    Keywords : ;

    Abstract : Drugs inhibiting the MAPK-pathway (MAPKi) and immune checkpoint inhibitors (ICI) have changed the clinical outcome of metastatic cutaneous malignant melanoma (CMM) in a significant way. Nonetheless, many patients have primary resistance or develop acquired resistance to these therapies within a relatively short period of time. READ MORE

  7. 25. Characteristics and functions of thymic exosomes in human and mouse

    Author : Gabriel Skogberg; Göteborgs universitet; []
    Keywords : MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; Exosome; thymus; tissue-restricted antigen; Aire; Down syndrome;

    Abstract : Thymocytes develop in the thymus to become a functional pool of T-cells in the periphery. To achieve this, the thymocytes go through several steps of maturation and selection within the thymus. READ MORE