Search for dissertations about: "microRNA"

Showing result 21 - 25 of 118 swedish dissertations containing the word microRNA.

  1. 21. Regulation of the myogenic response and stretch-induced calcium signaling in the vascular wall: Novel insights into the role of microRNAs and protein tyrosine kinase 2

    Author : Anirban Bhattachariya; Kärlfysiologi; []
    Keywords : MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; portal vein; resistance artery; myogenic tone; PYK2; calcium; microRNA;

    Abstract : Intraluminal pressure has a significant impact on vascular adaptability, phenotype and regulation of blood flow and pressure. On one hand, increased pressure/stretch for a prolonged time can cause structural changes in vessel wall; on the other hand, lack of pressure/stretch can promote a phenotype shift. READ MORE

  2. 22. Towards Better Understanding of Etiological Mechanisms at the Neuromuscular Junction

    Author : Evgenii Bogatikov; Anna Rostedt Punga; Klas Kullander; Viktorija Kenina; Uppsala universitet; []
    Keywords : MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; Neuromuscular junction; Muscle cells; Microelectrode array; MicroRNA; Clinical Neurophysiology; Klinisk neurofysiologi; Biomedical Laboratory Science; Biomedicinsk laboratorievetenskap;

    Abstract : The neuromuscular junction (NMJ) serves as a model for understanding the mechanisms that determine communication between neurons and their target cells. Disorders of the NMJ can be either autoimmune or genetic (hereditary). READ MORE

  3. 23. A microscopic investigation of miR-34c and miR-205 in Prostate Cancer

    Author : Zandra Hagman; Malmö Klinisk kemi; []
    Keywords : MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; microRNA; prostate cancer; androgen receptor; MET; HGF; miR-34c; miR-205; AGO2-RIP-Chip; noncoding RNA;

    Abstract : The complex genetics of cancer allows tumors to grow and spread undeterred by the control mechanisms of the cell. The importance of protein-coding genes in tumorigenesis is well established. READ MORE

  4. 24. Identification and Characterization of Proteins and MicroRNAs that Modulate Receptor Signaling, Vesicular Trafficking and Cell Migration in Vascular Cells

    Author : Johan Heldin; Johan Kreuger; Jonas Fuxe; Uppsala universitet; []
    Keywords : MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; Angiogenesis; cell migration; signaling; VEGF; FGD5; ExoC3L2; microRNA; RhoD; Molekylär cellbiologi; Molecular Cellbiology;

    Abstract : Blood vessels deliver nutrients and oxygen to tissues. Importantly, the functions and growth of blood vessels are commonly altered in disease. The inside of all blood vessels are lined with endothelium, a thin specialized layer of endothelial cells that separate the blood from other tissues. READ MORE

  5. 25. In vitro toxicity testing using human pluripotent stem cell derivatives

    Author : Gustav Holmgren; Anders Lindahl; Jane Synnergren; Peter Sartipy; Chris Denning; Sahlgrenska Academy at University of Gothenburg; []
    Keywords : NATURVETENSKAP; NATURAL SCIENCES; NATURVETENSKAP; NATURAL SCIENCES; MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; toxicity testing; human pluripotent stem cells; cardiomyocytes; hepatocytes; microarray; quantitative proteomics; bioinformatics; transcriptomics; microRNA; Medical sciences; Medicin; Bioinformatik; Bioinformatics;

    Abstract : .... READ MORE