Search for dissertations about: "microarray data analysis"

Showing result 1 - 5 of 162 swedish dissertations containing the words microarray data analysis.

  2. 1. Normalization and analysis of high-dimensional genomics data

    Author : Mattias Landfors; Patrik Rydén; Rebecka Jörnsten; Umeå universitet; []
    Keywords : NATURVETENSKAP; NATURAL SCIENCES; NATURVETENSKAP; NATURAL SCIENCES; normalization; pre-processing; microarray; downstream analysis; evaluation; sensitivity; bias; genomics data; gene expression; spike-in data; ChIP-chip; Mathematical Statistics; matematisk statistik;

    Abstract : In the middle of the 1990’s the microarray technology was introduced. The technology allowed for genome wide analysis of gene expression in one experiment. Since its introduction similar high through-put methods have been developed in other fields of molecular biology. READ MORE

  4. 2. Probalistic Methods In Genomic Data Analysis

    Author : Thomas Breslin; Beräkningsbiologi och biologisk fysik - Genomgår omorganisation; []
    Keywords : NATURVETENSKAP; NATURAL SCIENCES; pathway profiling; Bioinformatics; medical informatics; biomathematics biometrics; Bioinformatik; medicinsk informatik; differential gene expression; probabilistic methods; Natural science; Naturvetenskap; biomatematik; annotation analysis; microarray; Fysicumarkivet A:2004:Breslin;

    Abstract : In this thesis, three aspects of gene expression data analysis are discussed: Differential gene expression is addressed by a probabilistic method. Gene annotation enrichment analysis is discussed in the context of multiple hypothesis testing and the choice of null hypothesis. READ MORE

  5. 3. Statistical and Functional Analysis of Genomic and Proteomic Data

    Author : Yingchun Liu; Beräkningsbiologi och biologisk fysik - Genomgår omorganisation; []
    Keywords : NATURVETENSKAP; NATURAL SCIENCES; Bioinformatik; biomathematics biometrics; unsupervised classification; Bioinformatics; medical informatics; TGF-beta; linear mixed model; expression data; dye bias; 2D-gel; signaling pathway; regulatory motif; microarray; medicinsk informatik; biomatematik;

    Abstract : High-throughput technologies have led to an explosion in the availability of data at the genome scale. Such data provide important information about cellular processes and causes of human diseases, as well as for drug discovery. Deciphering the biologically relevant results from these data requires comprehensive analytical methods. READ MORE

  6. 4. Low-level analysis of microarray data

    Author : Henrik Bengtsson; Matematisk statistik; []
    Keywords : NATURVETENSKAP; NATURAL SCIENCES; programmering; aktuariematematik; Statistik; operationsanalys; Statistics; operations research; programming; actuarial mathematics;

    Abstract : This thesis consists of an extensive introduction followed by seven papers (A-F) on low-level analysis of microarray data. Focus is on calibration and normalization of observed data. The introduction gives a brief background of the microarray technology and its applications in order for anyone not familiar with the field to read the thesis. READ MORE

  7. 5. Weighted Analysis of Microarray Experiments

    Author : Anders Sjögren; Göteborgs universitet; []
    Keywords : MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; TEKNIK OCH TEKNOLOGIER; ENGINEERING AND TECHNOLOGY; NATURVETENSKAP; NATURAL SCIENCES; NATURVETENSKAP; NATURAL SCIENCES; DNA microarray; differential expression; gene expression; quality control QC ; quality assurance QA ; quality assessment; generalised linear model; empirical Bayes; weighted moderated statistic; invalid p-value; heteroscedasticity; WAME; heteroscedasticity;

    Abstract : DNA microarrays are strikingly efficient tools for analysing gene expression for large sets of genes simultaneously. The aim is often to identify genes which are differentially expressed between some studied conditions, thereby gaining insight into which cellular mechanisms are differently active between the conditions. READ MORE