Search for dissertations about: "microarray gene expression"
Showing result 1 - 5 of 360 swedish dissertations containing the words microarray gene expression.
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1. Microarray Based Gene Expression Analysis in Cancer Research
Abstract : Biotechnological inventions during the 20th century have resulted in a wide range of approaches for explorations in the functional genomics field. Microarray technology is one of the recent advances which have provided us with snapshots of which genes are expressed in cells of various tissues and diseases. READ MORE
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2. Contributions to Statistical Analysis of Gene Expression Data
Abstract : .... READ MORE
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3. Nonlinear dimensionality reduction of gene expression data
Abstract : Using microarray measurements techniques, it is possible to measure the activity of genes simultaneously across the whole genome. Since genes influence each others activity levels through complex regulatory networks, such gene expression measurements are state samples of a dynamical system. READ MORE
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4. Gene Expression Studies of Hematologic Malignacies
Abstract : The general aim of this thesis was to characterize hematologic malignancies using gene expression profiling in order to obtain an improved classification and to study deregulated transcriptional networks in leukemia. In the first study (Article I), the gene expression profiles of hematologic cell lines were analyzed to investigate whether such cell lines maintain expression profiles that are characteristic of their primary genetic changes. READ MORE
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5. Adipose tissue gene expression & candidate genes for obesity
Abstract : Obesity results from an interaction between genetic and environmental factors and is a growing health problem associated with development of insulin resistance, type 2 diabetes and cardiovascular disease. This thesis has focused on investigating the genetic contribution in obesity and insulin resistance by both candidate and global gene approaches with focus on the adipose tissue. READ MORE