Search for dissertations about: "microarray"

Showing result 11 - 15 of 599 swedish dissertations containing the word microarray.

2. 11. Microarray-based investigation of genome and transcriptome organisation in the archaeon sulfolobus

   Author : Anders Andersson; Joakim Lundeberg; Per Sunnerhagen; KTH; []
   Keywords : TEKNIK OCH TEKNOLOGIER; ENGINEERING AND TECHNOLOGY; Biotechnology; microarray; Sulfolobus; gene expression; archaea; mRNA decay; genome evolution; Bioteknik; Bioengineering; Bioteknik;

   Abstract : .... READ MORE

4. 12. Inflammatory response in the immature brainafter hypoxia-ischemia. Application of microarray and transgenic technology

   Author : Maj Hedtjärn; Göteborgs universitet; []
   Keywords : hypoxia-ischemia; neonatal; brain; inflammation; cytokine; IL-1; IL-18; microglia; ; gene; microarray;

   Abstract : Hypoxic-ischemic (HI) brain injury remains a common problem encountered during theneonatal period, and it is a major cause of perinatal mortality and long term neurologicalimpairments. After HI, an inflammatory reaction is elicited in the brain, which is believedto contribute to the secondary progression of brain injury. READ MORE

5. 13. Development and Application of Microarray-Based Comparative Genomic Hybridization : Analysis of Neurofibromatosis Type-2, Schwannomatosis and Related Tumors

   Author : Patrick Buckley; Jan Dumanski; Olivier Delattre; Uppsala universitet; []
   Keywords : MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; Genetics; Genomic microarray; Array-CGH; DNA copy number variation; Neurofibromatosis type-2; Schwannomatosis; Schwannoma; Meningioma; NF2; Chromosome 22; Genetik; Clinical genetics; Klinisk genetik;

   Abstract : Neurofibromatosis type-2 (NF2) is an autosomal dominant disorder with the clinical hallmark of bilateral eighth cranial nerve schwannomas. However, the diagnostic criterion is complicated by the presence of a variable phenotype, with the severe form presenting with additional tumors such as peripheral schwannoma, meningioma and ependymoma. READ MORE

6. 14. Development and Application of Human Chromosome 22 Genomic Microarray : Chromosome 22-Associated Disorders Analyzed by Array-Based Comparative Genomic Hybridization

   Author : Magdalena Benetkiewicz; Jan Dumanski; Niklas Dahl; Frank Speleman; Uppsala universitet; []
   Keywords : NATURVETENSKAP; NATURAL SCIENCES; Molecular genetics; DNA copy number changes; chromosome 22; genomic microarray; array-CGH; schwannoma; neurofibromatosis type 2; ovarian carcinoma; breast cancer; Wilms tumor; Genetik; Genetics; Genetik;

   Abstract : The array-based form of comparative genomic hybridization (array-CGH) is a new methodology that has shown to be of significant importance. This thesis focuses on the development of array-CGH with the aim to define candidate regions/genes on chromosome 22 in a wide spectrum of cancer-related conditions. READ MORE

7. 15. Transcript profiling of small tissue samples using microarray technology

   Author : Maria Sievertzon; Joakim Lundeberg; Tom Freeman; KTH; []
   Keywords : NATURVETENSKAP; NATURAL SCIENCES; Biology; Gene expression analysis; transcriptomics; microarray analysis; 3’-tag signature amplification; neural stem cells; Biologi; Biology; Biologi;

   Abstract : Through a number of biological, technological and computational achievements during the 20th century and the devoted work of hundreds of researchers the sequence of the human and other genomes are now available in public databases. The current challenge is to begin to understand the information encoded by the DNA sequence, to elucidate the functions of the proteins and RNA molecules encoded by the genes as well as how they are regulated. READ MORE