Search for dissertations about: "microinjection"

Showing result 1 - 5 of 18 swedish dissertations containing the word microinjection.

  1. 1. The Francisella pathogenicity island its role in type VI secretion and intracellular infection

    University dissertation from Umeå : Umeå University

    Author : Lena Meyer; Anders Sjöstedt; Siobhan C. Cowley; [2015]
    Keywords : MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; Francisella; FPI; Type VI Secretion; Igl; DotU; VgrG; Pdp; microinjection; phagosomal escape; intracellular replication; Clinical Bacteriology; klinisk bakteriologi;

    Abstract : Intracellular bacteria have developed various mechanisms to enter and persist in host cells and, at the same time, to evade the host immune response. One such pathogen is Francisella tularensis, the etiological agent of tularemia. READ MORE

  2. 2. Synaptic vesicle endocytosis studied in a living synapse

    University dissertation from Stockholm : Karolinska Institutet, Department of Neuroscience

    Author : Helge Gad; Karolinska Institutet.; Karolinska Institutet.; [2000]
    Keywords : MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; synapse; synaptic vesicles; endocytosis; clathrin; calcium; dynamin; endophilin; amphiphysin; synaptojanin; microinjection; electron microscopy;

    Abstract : Neurons in the central nervous system communicate by transmitting electrical signals at special sites of contact called synapses. Synapses contain neurotransmitter-filled synaptic vesicles, which fuse with the presynaptic plasma membrane. The neurotransmitter diffuses to the neighboring neuron and triggers a new electrical signal. READ MORE

  3. 3. Reciprocal interactions of neuropeptide y and angiotensin II receptors with a2-adrenoceptors in the nucleus tractus solitarii of the rat

    University dissertation from Stockholm : Karolinska Institutet, false

    Author : Shao-Nian Yang; Karolinska Institutet.; Karolinska Institutet.; [1996]
    Keywords : MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; Neuropeptide Y angiotensin II adrenaline noradrenaline; clonidinereceptor receptor-receptor interaction cardiovascular control immediate earlygene microinjection quantitative receptor autoradiographyimmunocytochemistry in situ hybridization ~ ;

    Abstract : -Neuropeptide Y (NPY), angiotensin II (Ang II) and adrenergictransmission lines in the nucleus tractus solitarii (NTS), the major relay nucleusinvolved in the cardiovascular reflex, play an important role in centralcardiovascular control. The present work explored reciprocal interactions of NPYand Ang II receptor subtypes with a2-adrenoceptors in the NTS of thenormotensive Sprague-Dawley rat (SD), the normotensive Wistar Kyoto rat(WKY) and the spontaneously hypertensive rat (SHR) by using a cardiovascularanalysis, quantitative receptor autoradiography, immunocytochemistry and in situhybridization techniques. READ MORE

  4. 4. Cytoskeletal mechanisms in synaptic vesicle recycling

    University dissertation from Stockholm : Karolinska Institutet, Department of Neuroscience

    Author : Jenny Gustafsson; Karolinska Institutet.; Karolinska Institutet.; [2003]
    Keywords : MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; Synapse; actin cytoskeleton; synaptic vesicle; endocytosis;

    Abstract : This thesis explores cytoskeletal mechanisms involved in the recycling of synaptic vesicles. As an initial step it characterizes synapses formed by giant reticulospinal axons in lamprey and defines their use as a model system. The most common type of reticulospinal synapse, "simple synapse", appeared to be most suitable as an experimental model. READ MORE

  5. 5. Cross-linked Profilin:actin - A tool to study actin dynamics in non-muscle cells

    University dissertation from Stockholm : Wenner-Grens institut för experimentell biologi

    Author : Staffan Grenklo; Roger Karlsson; Dan Lindholm; [2004]
    Keywords : NATURVETENSKAP; NATURAL SCIENCES; actin dynamics; profilin; actin; Profilin-actin complex; Cell motility; synaptic vesicle trafficing; Far western; fluorescence microscopy; NATURAL SCIENCES Biology Cell and molecular biology Cell biology; NATURVETENSKAP Biologi Cell- och molekylärbiologi Cellbiologi;

    Abstract : The microfilament system, consisting of actin and a number of auxiliary proteins, is fundamental for cell motility. Its dynamic organization depends on receptor-mediated signals, leading to rapid polymerizations and depolymerizations of actin. READ MORE