Search for dissertations about: "microsatellite analysis"

Showing result 1 - 5 of 92 swedish dissertations containing the words microsatellite analysis.

  2. 1. Approaches for analysis of mutations and genetic variations

    Author : Afshin Ahmadian; KTH; []
    Keywords : LOH; microsatellite; fragment analysis; DNA sequencing; pyrosequencing; cancer; mutation; variation; SNP; allele-specific extension; apyrase; TECHNOLOGY; TEKNIKVETENSKAP;

    Abstract : Detecting mutations and genomic variations is fundamental indiagnosis, isolating disease genes, association studies,functional genomics and pharmacogenomics. The objective hasbeen to use and further develop a variety of tools andtechnologies to analyze these genetic alterations andvariations. READ MORE

  4. 2. Genetic investigations of four neurological disorders : From phenotype to mutation

    Author : Anna Sillén; Uppsala universitet; []
    Keywords : MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; Pediatrics; genetic disease; chromosome; microsatellite; linkage analysis; mutation; Pediatrik; Paediatric medicine; Pediatrisk medicin; klinisk genetik; Clinical Genetics;

    Abstract : More than 5000, more or less rare, genetic diseases are known in man. A genetic disease is in most casesinherited from one generation to the next, and is caused by a change in the genetic code, a mutation. READ MORE

  5. 3. Genetic analysis of murine malaria

    Author : Susana Campino; Dan Holmberg; Nils Lycke; Umeå universitet; []
    Keywords : MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; Genetics; Malaria; genetic analysis; Plasmodium; wild derived inbred strains; loci; cerebral malaria; hyperparasitaemia.; Genetik; Clinical genetics; Klinisk genetik; genetik; Genetics;

    Abstract : Malaria, an infectious disease caused by Plasmodium parasites, is one of the major world-scale health problems. Despite the efforts aimed at finding an effective way to control the disease, the success has been thwarted by the emergence of parasite drug resistance and mosquito resistance to insecticides. READ MORE

  6. 4. Genetic and Genomic Analysis of Transcriptional Regulation in Human Cells

    Author : Mehdi Motallebipour; Claes Wadelius; Gunnar Westin; Dirk Schübeler; Uppsala universitet; []
    Keywords : MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; Transcription; ChIP-chip; ChIP-seq; genome-wide; transcription factors; microsatellite; epigenetic; Medical genetics; Medicinsk genetik;

    Abstract : There are around 20.000 genes in the human genome all of which could potentially be expressed. However, it is obvious that not all of them can be active at the same time. Thus, there is a need for coordination achieved through the regulation of transcription. READ MORE

  7. 5. Bioinformatic Analysis of Mutation and Selection in the Vertebrate Non-coding Genome

    Author : Mikael Brandström; Hans Ellegren; Diethard Tautz; Uppsala universitet; []
    Keywords : Biology; non-coding genome; selection; mutation; chicken; human; indel; microsatellite; sequence alignment; comparative genomics; bioinformatics; vertebrate; Biologi;

    Abstract : The majority of the vertebrate genome sequence is not coding for proteins. In recent years, the evolution of this noncoding fraction of the genome has gained interest. These studies have been greatly facilitated by the availability of full genome sequences. READ MORE