Search for dissertations about: "microsatellite haplotypes"

Showing result 1 - 5 of 14 swedish dissertations containing the words microsatellite haplotypes.

  2. 1. Factors Influencing Evolution to Antimalarial Drug Resistance in Plasmodium falciparum in Sudan and The Gambia

    Author : Amany Kheir; Göte Swedberg; Susanne Kerje; Hamza Babiker; Staffan Svärd; Uppsala universitet; []
    Keywords : MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; cross-mating; fitness; microsatellite haplotypes; mosquito infectivity; Infectious diseases; Infektionssjukdomar; Molekylär genetik; Molecular Genetics;

    Abstract : Drug resistance is a major obstacle to management and control of malaria and currently progressing at a rapid rate across Africa. This thesis has examined factors influencing evolution of resistant P. falciparum at two sites in Africa, including parasite migration, cross mating and fitness cost of resistance. READ MORE

  4. 2. Effects of Social Organisation on Spatial Genetic Structures in Formica Ants

    Author : Niclas Gyllenstrand; Michael Bruford; Uppsala universitet; []
    Keywords : NATURVETENSKAP; NATURAL SCIENCES; Biology; Formica ants; microsatellites; monogyny; mtDNA; polygyny; social insects; Biologi; Biology; Biologi; naturvårdsbiologi; Conservation Biology;

    Abstract : The social organization of social insect colonies can be broadly defined as monogynous, single reproductive female or polygynous, several reproductive females. Monogynous organization is genetically simple while polygynous is more complex and the two social forms differ commonly in mating and dispersal behaviour as well as in colony foundation. READ MORE

  5. 3. Hybridisation between introduced brown hares and native mountain hares in Sweden

    Author : Carl-Gustaf Thulin; Uppsala universitet; []
    Keywords : NATURVETENSKAP; NATURAL SCIENCES; Developmental biology; Utvecklingsbiologi; Developmental biology; Utvecklingsbiologi; naturvårdsbiologi; Conservation Biology;

    Abstract : To investigate the extent and effect of hybridisation between wild sympatric populations of introduced brown hares (Lepus europaeus) and native mountain hares (L.timidus) in Sweden, the geographic distribution of genetic variation in mitochondrial DNA (mtDNA) and nuclear DNA microsatellite markers were analysed within and between the two species and their presumed hybrids. READ MORE

  6. 4. Accessing Genetic Variation by Microarray Technology

    Author : Katarina Lindroos; Edwin Southern; Uppsala universitet; []
    Keywords : Medical sciences; microarrays; SNPs; minisequencing; four-colour detection; allele frequency; population study; evolutionary biology; MEDICIN OCH VÅRD; MEDICINE; MEDICIN; Molekylär medicin; Molecular Medicine;

    Abstract : Microarray technology is a promising approach for the simultaneous analysis of multiple single nucleotide polymorphisms (SNPs), which are the most abundant form of genetic variation. In this thesis enzyme-assisted microarray-based methods were developed to improve the accuracy and genotype discrimination power of the current methods for SNP genotyping. READ MORE

  7. 5. Immunoregulatory differences between adult onset type 1 diabetes and latent autoimmune diabetes in adults (LADA)

    Author : Magnus Hillman; Lund Medicin; []
    Keywords : MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; Endokrinologi; sekretion; diabetologi; diabetology; secreting systems; Isotype class switch; Endocrinology; LADA; Autoantibodies; Autoimmunity; Type 1 diabetes;

    Abstract : Autoimmune diabetes is characterized by cell mediated autoimmunity against insulin producing beta cells in pancreatic islets. Type 1 diabetes is the major cause of diabetes in children and adolescents and is believed to be mediated by a Thl driven destruction of beta cells. READ MORE