Search for dissertations about: "microsatellite instability"
Showing result 11 - 15 of 31 swedish dissertations containing the words microsatellite instability.
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11. Genotoxic effects of systemic chemotherapy in cancer patients - Microsatellite instability, loss of heterozygosity and expression of mismatch repair genes
Abstract : .... READ MORE
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12. Different genetic pathways involved in colorectal cancer
Abstract : Colorectal cancer (CRC) is one of the three leading causes of cancer mortality worldwide with an incidence of approximately one million cases and a mortality of 500 000 annually. Identification of different pathways involved in tumorigenesis of both familial and sporadic colorectal cancer may led to a major breakthrough in the prevention of this potentially curable disease. READ MORE
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13. Molecular genetic studies on Huntington disease
Abstract : Huntington disease (HD) is an autosomal dominant neurodegenerative disorder associated with an expanded trinucleotide repeat (CAG). Prior to the gene identification in 1993, linkage analysis was used for predictive testing for at-risk individuals. READ MORE
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14. Significance of molecular genetic alterations and apoptosis in colorectal cancer
Abstract : Colorectal cancer is a serious health problem in Western societies. In Sweden it is the second most common malignancy among females, and the third in males, and the third leading cause of cancer related death in both sexes. To date it is known that several biological pathways can lead to colorectal cancer. READ MORE
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15. Gastroesophageal reflux disease - complications and prognostic aspects
Abstract : This thesis investigates several aspects on gastroesophageal reflux disease (GERD) and associated complications as Barrett’s esophagus and esophageal adenocarcinoma. I. To clarify the natural course of GERD, a pH-metry verified cohort was re-evaluated after 20 years. The course of GERD may well be progressive. READ MORE