Search for dissertations about: "microvascular pathology"

Showing result 6 - 10 of 12 swedish dissertations containing the words microvascular pathology.

2. 6. Vascular inflammation : implications for microvascular reconstructive surgery after irradiation

   Author : Martin Halle; Karolinska Institutet; Karolinska Institutet; []
   Keywords : Inflammation; irradiation; atherosclerosis; NF-kappaB; nitric oxide; microvascular reconstructive surgery;

   Abstract : Better treatment has led to a rapidly increasing population of cancer survivors. A growing body of clinical evidence has shown that radiotherapy is associated with adverse effects on the cardiovascular system, such as myocardial infarction and stroke, depending on the previous treatment site. READ MORE

4. 7. Expression of TGF- isoforms, their receptors and related SMAD proteins in brain pathology : Immunohistochemical studies focusing on infarcts, abscesses and malignant gliomas

   Author : Ahmad Khaled Ata; Uppsala universitet; []
   Keywords : MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; Genetics; TGF-beta receptor; SMAD; brain; infarct; abscess; glioma; experimental; human; Genetik; Clinical genetics; Klinisk genetik; Genetics; genetik;

   Abstract : This thesis focuses on the immunohistochemical expression of transforming growth factor beta(TGFβ) isoforms, their receptors and TGF-β-related SMAD proteins in brain pathology, chiefly in-farcts. One key question was whether the expressions of these compounds are altered within glial cells, endothelial cells of microvessels and other cell types in the vicinity of infarcts. READ MORE

5. 8. Peripheral polyneuropathy in type 2 diabetes mellitus and impaired glucose tolerance. Correlations between morphology, neurophysiology, and clinical findings

   Author : Soley Thrainsdottir; Sektion IV; []
   Keywords : MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; nerve conduction studies; skin biopsy; intraepidermal nerve fibers; Diabetic neuropathy; sural nerve pathology; body mass index; quantitative sensory testing; vibrotactile sense;

   Abstract : Diabetic peripheral polyneuropathy (PN) is a common and serious complication of diabetes. The prevalence of PN is rising with the global burden of type 2 diabetes. The causal mechanisms of PN are not fully understood, but both vascular and metabolic factors play a role. READ MORE

6. 9. Extracellular Matrix and Connective Tissue Cells of the Tumor Microenvironment

   Author : Tomas Friman; Christian Sundberg; Kristofer Rubin; Ulf Eriksson; Uppsala universitet; []
   Keywords : MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; Biochemistry; Biokemi; Morphology; cell biology; pathology; Morfologi; cellbiologi; patologi; Tumour biology; Tumörbiologi; Medical Science; Medicinsk vetenskap;

   Abstract : In addition to malignant cells, solid tumors comprise supporting stromal tissue that consists of extra cellular matrix (ECM), connective tissue cells, inflammatory cells and blood vessels. The stromal compartment and the malignant cells together shape the tumor microenvironment that in turn determines tumor progression and efficacy of anti-tumor treatments. READ MORE

7. 10. Non-invasive assessment of dynamic properties in human arteries : with special reference to gestation and diabetes

   Author : Jie Hu; Karolinska Institutet; Karolinska Institutet; []
   Keywords : Acetylcholine; Adolescents; Aorta; Diameter waveforms; Diameter pulse waves; Echo tracking system; Fetal behavioural state; Fetal breathing movements; Gestational diabetes mellitus; Impending birth; Insulin-dependent diabetes mellitus; Laser Doppler; Microcirculation; Pregnancy; Pulse wave velocity; Vascular endothelium; Vascular stiffness; Ultrasound;

   Abstract : Background: The important role played by the intrinsic properties of central arteries in cardiovascular physiology and pathology has been increasingly recognised. Several circulatory disorders are associated with increased arterial stiffness. READ MORE