Search for dissertations about: "microwell"

Showing result 1 - 5 of 12 swedish dissertations containing the word microwell.

  1. 1. Miniaturised Microwell-based Cell Assays

    University dissertation from Stockholm : KTH Royal Institute of Technology

    Author : Emilie Weibull; Helene Andersson Svahn; Albert van den Berg; [2014]
    Keywords : MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; microwell; miniaturisation; high-resolution imaging; high-throughput; cell culture; single-cell; clone; heterogeneity; antibiotic susceptibility testing; concentration gradient; interfacing; microchannels; cell retrieval;

    Abstract : Cell heterogeneity in genetically identical cell populations is becoming a well-known and important phenomenon in cell biology. Current methods commonly utilise population-based analysis founded on averaged result. Hence there is a need for high-throughput cell assays on the single-cell level. READ MORE

  2. 2. Microwell devices for single-cell analyses

    University dissertation from Stockholm : KTH

    Author : Sara Lindström; Helene Andersson-Svahn; Mehmet Toner; [2009]
    Keywords : NATURVETENSKAP; NATURAL SCIENCES; microwell; miniaturization; microfluidics; cell culture; single-cell; clone; imaging; stem cell; cancer; low volume; high-throughput; NATURAL SCIENCES Biology Cell and molecular biology Molecular biology; NATURVETENSKAP Biologi Cell- och molekylärbiologi Molekylärbiologi;

    Abstract : Powerful tools for detailed cellular studies are emerging, increasing the knowledge ofthe ultimate target of all drugs: the living cell. Today, cells are commonly analyzed inensembles, i.e. thousands of cells per sample, yielding results on the average responseof the cells. READ MORE

  3. 3. Genital human papillomaviruses. Studies of their occurrence, type spectrum and expression

    University dissertation from Virology

    Author : Ola Forslund; [1997]
    Keywords : MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; mRNA expression; microwell; HPV 70; type determination; CIN; quantification; urine; multifocal infections; hybridization; PCR; HPV; human papillomavirus; Microbiology; bacteriology; virology; mycology; Mikrobiologi; bakteriologi; virologi; mykologi;

    Abstract : The occurrence of genital human papillomavirus infection was determined in different categories of patients by means of PCR. In high proportion of young women attending an adolescent clinic, the presence of HPV DNA was demonstrated in simultaneously urethral and cervical samples, suggesting that genital HPV infections are often multifocal. READ MORE

  4. 4. Digital Electrical DNA Sensing

    University dissertation from Stockholm : KTH Royal Institute of Technology

    Author : Maoxiang Guo; Wouter van der Wijngaart; Fredrik Westerlund; [2019]
    Keywords : TEKNIK OCH TEKNOLOGIER; ENGINEERING AND TECHNOLOGY; MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; DNA detection; thiol-ene-epoxy; rolling circle amplification; digital measurement; DNA stretching; microwell-array; gold nanowires; electrical measurement; specificity; limit of detection; liquid storage; disease diagnosis; lab-on-a-chip; point-of-care.;

    Abstract : Molecule detection is a workhorse in life sciences and medicine, for example in cancer diagnosis and virus and bacterial detection. DNA analysis can provide vital information about the state of a host organism and its medical and health condition. READ MORE

  5. 5. Single cell studies of human T cell function with applications for HIV-1

    University dissertation from Stockholm : Karolinska Institutet, Dept of Laboratory Medicine

    Author : Johanna Tauriainen; Karolinska Institutet.; Karolinska Institutet.; [2016]
    Keywords : MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES;

    Abstract : T cells are one of the body’s main defenses against viruses and cancers and are therefore considered to play a major role in immunotherapies after stem cell transplantation and in HIV-1 vaccine and cure strategies. However, malignancies and chronic viral infections, such as HIV-1, eventually cause the T cells to become dysfunctional, resulting in a loss of control. READ MORE