Search for dissertations about: "migration on extracellular"

Showing result 6 - 10 of 148 swedish dissertations containing the words migration on extracellular.

  2. 6. Migration of Natural Killer Cells. Matrix interaction, locomotion and regulation of matrix metalloproteinases (MMPs) by IL-2 and chemokines

    Author : Karin Edsparr; Göteborgs universitet; []
    Keywords : NK cell; MMP; Matrigel; migration; IL-2;

    Abstract : Activated natural killer (NK) cells are effective anti-tumour cells. In order to reach target cells in a tumour mass they need to migrate in the extravascular space. READ MORE

  4. 7. Reversal of thyroid dedifferentiation and an invasive phenotype by small molecule kinase inhibitors: an experimental study on normal and malignant cells

    Author : Camilla Ingeson-Carlsson; Göteborgs universitet; []
    Keywords : MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; thyroid; cancer; NIS; MAPK; PI3K; BRAFV600E; migration; 3D culture;

    Abstract : Refractoriness to I-131 in dedifferentiated thyroid cancer is a great concern that restricts radioiodine therapy. There is also a lack of knowledge in understanding the mechanisms leading to repressed sodium iodide symporter (NIS) expression and impaired iodide uptake in tumor cells. READ MORE

  5. 8. Stem cells : proliferation, differentiation, migration

    Author : Anna Falk; Karolinska Institutet; Karolinska Institutet; []
    Keywords : Embryonic stem cell; adult neural stem cells; proliferation; differentiation; migration;

    Abstract : A stem cell is demanding and requires precise conditions to carry out its unique tasks. This includes proliferation as an undifferentiated stem cell, differentiation to more mature cell types, migration through tissue to its final destination, and functional integration into the cellular network. READ MORE

  6. 9. Tissue Factor in Transplantation -aspects on expression and inhibition

    Author : Cecilia Österholm; Kirurgi; []
    Keywords : MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; nephrotoxicity; tissue factor; transplantation; ischemia-reperfusion injury; serologi; Immunologi; serology; Immunology; extracellulära vätskor; Hematologi; extracellular fluids; traumatology; Kirurgi; Urology; nephrology; Urologi; nefrologi; Surgery; orthopaedics; ortopedi; traumatologi; Haematology; chronic rejection;

    Abstract : Organ transplantation provides a treatment of end-stage disease primarily in the kidney, liver and heart. The immunosuppressive treatment regimens of today efficiently prevent early acute rejection; however the long-term survival has not improved to the same extent. READ MORE

  7. 10. Proteins of the Inter-α-inhibitor Family : Biosynthesis, Plasma Clearance and Interaction with Extracellular Matrix Components

    Author : Aneta Kaczmarczyk; Erik Fries; Anders Malmström; Uppsala universitet; []
    Keywords : NATURVETENSKAP; NATURAL SCIENCES; Biochemistry; bikunin; inter-α-inhibitor; pre-α-inhibitor; intracellular processing; plasma clearance; extracellular matrix; binding; collagen; Biokemi; Biochemistry; Biokemi; Medical Biochemistry; medicinsk biokemi;

    Abstract : Bikunin, a chondroitin sulfate-containing protein of 25 kDa, has protease inhibitory activity and occurs in the plasma in free and complexed form. In inter-α-inhibitor (IαI) and pre-a-inhibitor (PαI) it is covalently linked through its chondroitin sulfate (CS) chain to two or one other polypeptide of about 80 kDa – heavy chains 1 and 2 (H1, H2) and heavy chain 3 (H3) – respectively. READ MORE