Search for dissertations about: "mikko"

Showing result 1 - 5 of 35 swedish dissertations containing the word mikko.

  1. 1. Visualization of Peripheral Pain Generating Processes and Inflammation in Musculoskeletal Tissue using [11C]-D-deprenyl PET

    Author : Mikko Aarnio; Torsten Gordh; Jens Sörensen; Magnus Peterson; Lars Ståhle; Uppsala universitet; []
    Keywords : MEDICAL AND HEALTH SCIENCES; MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; MEDICIN OCH HÄLSOVETENSKAP; MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; ankle injuries; arthritis; binding site; binding target; carbon-11; deprenyl; high-throughput screening; inflammation; monoamine oxi-dase; pain; PET; whiplash; Anestesiologi och intensivvård; Anaesthesiology and Intensive Care;

    Abstract : An objective visualization and quantification of pain-generating processes in the periphery would alter pain diagnosis and represent an important paradigm shift in pain research. Positron emission tomography (PET) radioligand [11C]-D-deprenyl has shown an elevated uptake in painful inflammatory arthritis and whiplash-associated disorder. READ MORE

  2. 2. Effects of lipid oxidation on transcriptional regulation and cell death

    Author : Mikko Ares; Karolinska Institutet; Karolinska Institutet; []
    Keywords : atherosclerosis; low density lipoprotein; lipid oxidation; nuclear factor-KB; activator protein-1; Iysophosphatidylcholine; tumor necrosis factor-alpha; oxysterol; Ca2 ; apoptosis; lipid accumulation;

    Abstract : Elevated levels of low density lipoprotein (LDL) in plasma are associated with an increased risk for atherosclerosis. Excessive accumulation of lipoproteins and lipids in the vascular wall is thought to lead to the development of advanced atherosclerotic lesions prone to rupture. READ MORE

  3. 3. Development of the Lund AMS facility for the detection of Al-26 -- with applications in plant ecology

    Author : Mikko Faarinen; Kärnfysik; []
    Keywords : NATURVETENSKAP; NATURAL SCIENCES; NATURVETENSKAP; NATURAL SCIENCES; ion source; injector; plant material; Nuclear physics; Kärnfysik; aluminium; Accelerator mass spectrometry; AMS; Fysicumarkivet A:2003:Faarinen;

    Abstract : Accelerator mass spectrometry (AMS) is a highly sensitive technique to count atoms. The method has a high efficiency, which makes it possible to measure small samples in a relatively short time, usually less than an hour. During the work for this thesis, methods have been developed to detect Al-26 at the Lund AMS facility. READ MORE

  4. 4. Enzymatic studies of alcohol dehydrogenase by a combination of in vitro and in silico methods

    Author : Mikko Hellgren; Karolinska Institutet; Karolinska Institutet; []
    Keywords : ;

    Abstract : The family of alcohol dehydrogenases (ADHs) catalyzes conversions of alcohols, ketons and aldehydes. The early discovery and isolation of ADH (1937) was followed by numerous investigations. It was also the first dimeric enzyme for which the threedimensional structure was determined (1974). READ MORE

  5. 5. “Self-discipline strategies were easy to design but difficult to adhere to” : A Usage-Based Study of the Tough Construction in English

    Author : Mikko Höglund; Juhani Rudanko; Christian Mair; University of Tampere; []

    Abstract : .... READ MORE