Search for dissertations about: "mirna and cancer"
Showing result 1 - 5 of 61 swedish dissertations containing the words mirna and cancer.
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1. Bioinformatics tools for discovery and evaluation of biomarkers : Applications in clinical assessment of cancer
Abstract : Cancer is a disease characterized by abnormal proliferation of cells in the body and ranks as the second leading cause of death worldwide. In order to improve cancer patient care, a major focus of cancer research is to discover biomarkers. READ MORE
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2. Molecular understanding of KRAS- and BRAF-mutated colorectal cancers
Abstract : Colorectal cancer (CRC) is the third most commonly diagnosed malignancy in both men and women, and one of the leading causes of cancer-related deaths worldwide. One frequently mutated pathway involved in oncogenesis in CRC is the RAS/RAF/MAP kinase pathway. READ MORE
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3. Cell cycle regulatory proteins and miRNAs in premalignant lesions and breast cancer
Abstract : Early diagnosis and reliable prognosis and treatment prediction of breast cancer will ultimately lead to a decreased mortality rate. This can be achieved by identification of prognostic and treatment predictive biomarkers, and by understanding the mechanisms behind early changes in the breast. READ MORE
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4. Non-coding RNAs and Extracellular Vesicles in Cutaneous Squamous Cell Carcinoma
Abstract : Cutaneous squamous cell carcinoma (cSCC) ranks among the most widespread malignancies with metastatic potential. Investigating the molecular mechanism of tumorigenesis will enhance our understanding of cSCC. Aberrant expression of non-coding RNAs has been extensively reported in human cancers. READ MORE
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5. Myofibroblasts and the Vascular Endothelium : Impact of Fibrin Degradation Products and miRNA on Vascular Motility and Function
Abstract : Angiogenesis is the formation of new blood vessels from pre-existing vasculature and is important during development as well as wound healing and tissue remodeling. Angiogenesis also occurs during pathological conditions such as diabetic retinopathy and cancer. READ MORE