Search for dissertations about: "mitochondria turnover"

Showing result 1 - 5 of 12 swedish dissertations containing the words mitochondria turnover.

  2. 1. Muscle mitochondria in sepsis

    Author : Katarina Fredriksson; Karolinska Institutet; Karolinska Institutet; []
    Keywords : ;

    Abstract : Patients treated in the intensive care unit (ICU) for sepsis induced multiple organ failure often suffer from skeletal muscle fatigue after ICU discharge. Since mitochondria are the main determinants of muscle fatigability, their function in muscle of these patients was the theme of this thesis. READ MORE

  4. 2. Regulation of proton-coupled electron transfer in cytochrome c oxidase : The role of membrane potential, proton pathways and ATP

    Author : Markus Björck; Peter Brzezinski; Thorsten Friedrich; Stockholms universitet; []
    Keywords : NATURVETENSKAP; NATURAL SCIENCES; cytochrome c oxidase; charge transfer; membrane potential; membrane protein; mitochondria; ATP; proton pump; Biochemistry; biokemi;

    Abstract : Cytochrome c oxidase (CytcO) is the final electron acceptor of the respiratory chain. In this chain a current of electrons, derived from degradation of nutrients, along with protons, are used to reduce oxygen to water. The reaction is exergonic and the excess energy is used to pump protons across the membrane. READ MORE

  5. 3. Interconnectivity of mitochondrial protein biogenesis and homeostasis

    Author : Carmela Vázquez Calvo; Martin Ott; Jan Riemer; Stockholms universitet; []
    Keywords : NATURVETENSKAP; NATURAL SCIENCES; mitochondria; proteostasis; protein quality control; chaperones; biokemi; Biochemistry;

    Abstract : To ensure correct protein function, the cells are equipped with a tightly regulated network of chaperones that support protein folding and actively participate in protein quality control (PQC) and turnover. Due to the dual origin of the mitochondrial proteome, the cytosolic and mitochondrial PQC networks coordinate to ensure protein import and assembly in the organelle. READ MORE

  6. 4. Pyridine Nucleotides in Plant Mitochondria. Amounts, metabolism and contribution to electron transport

    Author : Stephanie C Agius; Biologiska institutionen; []
    Keywords : NATURVETENSKAP; NATURAL SCIENCES; Växtbiokemi; Plant biochemistry; antibody; Botanik; NAD-pyrophosphatase; Botany; NADH:ubiquinone oxidoreductase; NADPH dehydrogenase; plant mitochondria; pyridine nucleotides;

    Abstract : HPLC analysis was used for direct quantification of amounts and redox levels of pyridine nucleotides in plant mitochondria. The amount of NAD(H) and NADP+ varied, 1.0-3.7 and 0-0. READ MORE

  7. 5. From nucleus to mitochondria : a ubiquitination study

    Author : Thibaud J C Richard; Karolinska Institutet; Karolinska Institutet; []
    Keywords : ;

    Abstract : Ubiquitination is a post-translational modification achieved by an enzymatic cascade. This post-translational modification is involved in many crucial cellular processes across different cellular compartments such as protein turnover via the ubiquitin proteasome system and various signaling pathways from the DNA damage response to the immune response. READ MORE