Search for dissertations about: "mitochondrial cardiomyopathy"
Showing result 1 - 5 of 10 swedish dissertations containing the words mitochondrial cardiomyopathy.
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1. Crisis in Energy Metabolism - Mitochondrial Defects and a New Disease Entity
Abstract : Impairment of energy metabolism may be associated with severe implications for affected individuals since all fundamental cell functions are energy-dependent. Disorders of energy metabolism are often genetic and associated with defects in the oxidative phosphorylation in mitochondria. READ MORE
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2. Life without mitochondrial DNA : studies of transgenic mice
Abstract : Mitochondrial DNA (mtDNA) is a closed circular DNA genome that resides in the mitochondrial network. Mutations of mtDNA cause spontaneous and hereditary disorders known as mitochondrial diseases. Mitochondrial transcription factor A (Tfam) is a key factor for transcription of mtDNA in vitro. READ MORE
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3. Regulation of mitochondrial gene expression in metazoa
Abstract : Mitochondria are essential organelles of eukaryotic cells and their main function is to provide the cell with the ubiquitously used energy currency ATP. Impaired energy conversion caused by mitochondrial dysfunction is a direct cause of several human diseases. READ MORE
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4. Cellular responses to respiratory chain dysfunction
Abstract : Mitochondria are network-like organelles present in most mammalian cells. They contain the respiratory chain (RC) that produces the majority of the energy needed in the cell, in the form of ATP. RC deficiency can arise due to mutations in the mitochondrial DNA (mtDNA) or in nuclear genes encoding mitochondrial proteins. READ MORE
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5. From gene mutation to gene expression : studies on multiple endocrine neoplasia type 1 and vascular endothelial growth factors
Abstract : Multiple Endocrine Neoplasia type 1, MEN1, is an inherited cancer syndrome whose gene was localised to chromosome 11q13 in 1988. A number of !candidate genes were characterised before the MEN1 gene was cloned in 1997. DNA sequencing of MEN1 to search for mutations in patients is used as a complement to clinical diagnosis. READ MORE