Search for dissertations about: "mitochondrial dynamics"

Showing result 1 - 5 of 45 swedish dissertations containing the words mitochondrial dynamics.

  2. 1. Cell signaling by Rho and Miro GTPases : Studies of Rho GTPases in Cytoskeletal Reorganizations and of Miro GTPases in Mitochondrial Dynamics

    Author : Åsa Fransson; Pontus Aspenström; Harry Mellor; Uppsala universitet; []
    Keywords : NATURVETENSKAP; NATURAL SCIENCES; Ras superfamily; Rho GTPases; cytoskeleton; Miro GTPases; mitochondrial dynamics; Cell and molecular biology; Cell- och molekylärbiologi;

    Abstract : The Ras superfamily of GTPases embraces six major branches of proteins: the Ras, Rab, Ran, Arf, Rho and Miro subfamilies. The majority of GTPases function as binary switches that cycle between active GTP-bound and inactive GDP-bound states. This thesis will focus primarily on the biological functions of the Rho and Miro proteins. READ MORE

  4. 2. Characterization of mitochondrial membrane proteins as novel components in mitochondrial dynamics

    Author : Tong Liu; Karolinska Institutet; Karolinska Institutet; []
    Keywords : ;

    Abstract : Mitochondria are dynamic organelles that frequently change their shape by shifting the balance of fusion and fission in response to cellular metabolic needs. This process is termed mitochondrial dynamics. Dysregulation of mitochondrial dynamics has been described in many human diseases. READ MORE

  5. 3. Molecular mechanisms of human mitochondrial dynamics : inspiration and challenge

    Author : Rong Yu; Karolinska Institutet; Karolinska Institutet; []
    Keywords : ;

    Abstract : Mitochondria are highly dynamic organelles in cells. They frequently change the morphology via continuous fission and fusion events, referred to as mitochondrial dynamics, which includes the shape, size and number of mitochondria in the cell, as well as mitochondrial subcellular distribution and mitochondrial quality control. READ MORE

  6. 4. Peering Beyond the Noise in Experimental Biophysical Data

    Author : Dari Kimanius; Erik Lindahl; Holger Stark; Stockholms universitet; []
    Keywords : NATURVETENSKAP; NATURAL SCIENCES; Cryo-EM; mitochondrial ribosome; SAXS; molecular dynamics; metadynamics; Biochemistry towards Bioinformatics; biokemi med inriktning mot bioinformatik;

    Abstract : Experimental protein structure determination methods make up a fundamental part of our understanding of biological systems. Manual interpretation of the output from these methods has been made obsolete by the sheer size and complexity of the acquired data. READ MORE

  7. 5. From Structure to Function with Binding Free Energy Calculations for Codon Reading, Riboswitches and Lectins

    Author : Johan Sund; Åqvist Johan; Javier Luque; Uppsala universitet; []
    Keywords : NATURVETENSKAP; NATURAL SCIENCES; binding free energy; ribosome; codon reading; release factor; mitochondrial translation; purine riboswitch; lectin; molecular dynamics; free energy perturbation; Biology with specialization in Structural Biology; Biologi med inriktning mot strukturbiologi;

    Abstract : Molecular association is part of many important processes in living cells. Computational methods for calculating binding free energies allows for a quantitative examination of biomolecular structures and hypotheses drawn from biochemical experiments. READ MORE