Search for dissertations about: "mitochondrial genes"

Showing result 1 - 5 of 177 swedish dissertations containing the words mitochondrial genes.

  1. 1. Mitochondrial Evolution Turning Bugs into Features

    University dissertation from Uppsala : Acta Universitatis Upsaliensis

    Author : Olof Karlberg; Uppsala universitet.; [2004]
    Keywords : NATURVETENSKAP; NATURAL SCIENCES; Biology; Biologi; NATURAL SCIENCES Biology; NATURVETENSKAP Biologi;

    Abstract : The bacterial origin of mitochondria from an ancient endosymbiosis is now widely accepted and the mitochondrial ancestor is generally believed to belong to the bacterial subdivision α-proteobacteria. The high fraction of mitochondrial proteins encoded in the nucleus has commonly been explained with a massive transfer of genes from the genome of the ancestral mitochondrion. READ MORE

  2. 2. Genotypic and phenotypic spectrum of mitochondrial diseases with focus on early onset mitochondrial encephalopathies

    University dissertation from Göteborg : University of Gothenburg

    Author : Kalliopi Sofou; Göteborgs universitet.; Gothenburg University.; [2014]
    Keywords : MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; Mitochondrial diseases; mitochondrial encephalopathy; Alpers syndrome; Leigh syndrome; neuroimaging; whole exome sequencing;

    Abstract : Early-onset mitochondrial encephalopathies comprise a challenging group of neurodegenerative disorders. This is due to their progressive nature, often leading to major disability and premature death, as well as their diagnostic complexity and lack of customized treatments. READ MORE

  3. 3. Identification of abnormally expressed genes in skeletal muscle contributing to insulin resistance and type 2 diabetes

    University dissertation from Xudong Huang, Wallenberg Laboratory, MAS 46 P 3, Malmö 20502

    Author : Xudong Huang; [2002]
    Keywords : MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; Endocrinology; secreting systems; diabetology; Endokrinologi; gene expression; high-fat intake; RT-PCR; mitochondrial genes; cathepsin L; Shc; IRS-2; IRS-1; GS; cDNA differential display; Insulin resistance; type 2 diabetes; sekretion; diabetologi;

    Abstract : The metabolic defects of insulin resistance and type 2 diabetes can result from changes in gene expression and protein functions due to genetic and environmental influences. The aim of this study was to identify abnormally expressed genes associated with insulin resistance or type 2 diabetes, and further to test whether possible defects are inherited or acquired. READ MORE

  4. 4. Transcriptional regulation of human nuclear encoded mitochondrial genes

    University dissertation from Stockholm : Stockholm University

    Author : Ahmed Zaid; [2001]
    Keywords : NATURVETENSKAP; NATURAL SCIENCES; biokemi; Biochemistry;

    Abstract : Biogenesis of mammalian mitochondria requires the participation of both nuclear and mitochondrial genes. This thesis presents studies that characterize the common features of several nuclear encoded mitochondrial promoter genes and proposes the identity of factors regulating the transcription and responsible for coordinated, constitutive expression of diverse mammalian oxidative phosphorylation (OXPHOS) genes. READ MORE

  5. 5. Transcriptional regulation of some nuclear-encoded mitochondrial genes

    University dissertation from Stockholm : Stockholm University

    Author : Li Ronggui; Stockholms universitet.; [1998]
    Keywords : NATURVETENSKAP; NATURAL SCIENCES; biokemi; Biochemistry;

    Abstract : .... READ MORE