Search for dissertations about: "mitochondrial genomes"
Showing result 11 - 15 of 43 swedish dissertations containing the words mitochondrial genomes.
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11. Molecular insights into primer removal during mtDNA replication
Abstract : Mitochondria are vital for cell survival, and the primary producers of ATP, the energy currency used for various metabolic processes. Mitochondria are unique from other cellular compartments because they have their own genomes of circular small double-stranded DNA (mtDNA) of approximately 16. READ MORE
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12. Insights into the roles of the essential Pfh1 DNA helicase in the nuclear and mitochondrial genomes
Abstract : Eukaryotic cells have two sets of genomes, the nuclear and mitochondrial, and both need to be accurately maintained. Also, the rate of transcription must be precisely regulated in these genomes. However, there are many natural barriers that dysregulate these processes. READ MORE
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13. Biochemical studies of mitochondrial DNA maintenance and topology
Abstract : Mitochondria are crucial organelles in eukaryotic cells that produce the majority of adenosine trisphosphate used by cells as an energy currency to drive metabolic processes. Due to the endosymbiotic origin of mitochondria, they have their own genetic material, a small circular double-stranded molecule (mtDNA) of 16. READ MORE
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14. The interface of mitochondrial DNA transcription and replication
Abstract : Mitochondria are a dynamic network of subcellular organelles that produce the majority of cellular ATP through the process of oxidative phosphorylation (OXPHOS). The components of the respiratory chain are encoded by two separate genomes, nuclear DNA and mitochondrial DNA (mtDNA), and the proper maintenance of both of these genomic entities is therefore crucial for cellular ATP levels and the survival of the cell. READ MORE
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15. Reconstructing the Human Past using Ancient and Modern Genomes
Abstract : The study of DNA variation is one of the most promising avenues for learning about the evolutionary and historical past of humans and other species. However, the difficulty associated with obtaining DNA directly from ancient remains have for long kept genomic studies of population history trapped in time; confined to interpreting patterns of modern-day variation without direct historical observations. READ MORE