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Found 3 swedish dissertations matching the above criteria.

  1. 1. Structural characterisation of mitochondrial macromolecular complexes using cryo-EM : Mitoribosome biogenesis and respiratory chain supercomplex

    Author : Sorbhi Rathore; Martin Ott; Daniel Wilson; Stockholms universitet; []
    Keywords : NATURVETENSKAP; NATURAL SCIENCES; NATURVETENSKAP; NATURAL SCIENCES; Mitochondria; mitoribosome biogenesis; mitoribosome assembly factors; yeast respiratory supercomplexes; single particle electron cryo-microscopy; cryo-EM sample preparation; Biochemistry; biokemi;

    Abstract : Mitochondria, popularly known as powerhouse of the cell, contain specialised mitoribosomes that synthesise essential membrane proteins. These essential proteins are required to form enzyme complexes, which carry out the process of oxidative phosphorylation (OXPHOS). READ MORE

  2. 2. The mitoribosome as a hub for integrating mitochondrial gene expression : Regulation of translation and early assembly of cytochrome b

    Author : Andreas Carlström; Martin Ott; Chris Meisinger; Stockholms universitet; []
    Keywords : NATURVETENSKAP; NATURAL SCIENCES; mitochondria; gene expression; mitochondrial ribosome; translation regulation; feedback loop; biokemi; Biochemistry;

    Abstract : The mitochondrial proteome is a mosaic of proteins from two different genetic systems. The majority of mitochondrial proteins are encoded in the nuclear genome and are synthesized in the cytosol before imported to mitochondria. READ MORE

  3. 3. Characterization of GTPBPs involved in ribosome assembly and function in human mitochondria

    Author : Miriam Cipullo; Karolinska Institutet; Karolinska Institutet; []
    Keywords : ;

    Abstract : Mitochondria are organelles often referred to as the powerhouses of the cell as they provide most of the chemical energy via aerobic respiration. However, in the last half a century, it has become clear that their function extends to other fundamental metabolic tasks. READ MORE