Search for dissertations about: "mitosis"

Showing result 1 - 5 of 110 swedish dissertations containing the word mitosis.

  1. 1. Adhesion-dependent mechanisms regulating mitosis

    Author : Deepesh Kumar Gupta; Staffan Johansson; Kaisa Haglund; Uppsala universitet; []
    Keywords : NATURAL SCIENCES; NATURVETENSKAP; NATURAL SCIENCES; NATURVETENSKAP; Cytokinesis; Centrosome; Septin; Abscission; Mitosis; Integrin; Adhesion; Binucleation; Biokemi; Biochemistry;

    Abstract : Integrin-mediated cell adhesion is required for normal cell cycle progression during G1-S transition and for the completion of cytokinesis. Cancer cells have ability to grow anchorage-independently, but the underlying mechanisms and the functional significance for cancer development are unclear. READ MORE

  2. 2. The roles of inner nuclear membrane proteins during interphase and mitosis

    Author : Veronica J. Larsson; Einar Hallberg; Neus Visa; Stockholms universitet; []
    Keywords : MEDICAL AND HEALTH SCIENCES; MEDICIN OCH HÄLSOVETENSKAP; MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; Samp1; mitotic spindle; centrosome; LINC complex; Lamina; Sun1; mitosis; neurokemi med molekylär neurobiologi; Neurochemistry with Molecular Neurobiology;

    Abstract : The nuclear envelope (NE) consists of two concentric membranes, the outer nuclear membrane (ONM) and the inner nuclear membrane (INM). The LINC (linker of nucleoskeleton and cytoskeleton) complex spans both the ONM and the INM connecting the cytoskeleton to the nucleoskeleton and chromatin. READ MORE

  3. 3. Host epithelium integrity in the female reproductive tract during Neisseria gonorrhoeae infection

    Author : Linda Weyler; Helena Aro; Lene Rasmussen; Stockholms universitet; []
    Keywords : NATURAL SCIENCES; NATURVETENSKAP; NATURVETENSKAP; NATURAL SCIENCES; Female reproductive tract; Neisseria gonorrhoeae; VK2 E6E7 cells; DNA damage; cell cycle; mitosis; restriction endonucleases; infection models; molekylär biovetenskap; Molecular Bioscience;

    Abstract : Neisseria gonorrhoeae infections are asymptomatic in approximately fifty percent of the affected women. Left untreated, this can develop into a long-term inflammatory state with detrimental secondary complications such as ectopic pregnancy and sterility. Furthermore, studies have shown that N. READ MORE

  4. 4. DNA Damage Response of Normal Epidermis in the Clinical Setting of Fractionated Radiotherapy : Evidence of a preserved low-dose hypersensitivity response

    Author : Fredrik Qvarnström; Ingela Turesson; Gunilla Enblad; Mats Harms-Ringdahl; Uppsala universitet; []
    Keywords : MEDICAL AND HEALTH SCIENCES; MEDICIN OCH HÄLSOVETENSKAP; MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; DNA damage response; low-dose hypersensitivity; dose response; normal tissue; epidermis; keratinocyte; fractionated radiotherapy; DNA double strand break; DSB; foci; γH2AX; 53BP1; checkpoint; p21; apoptosis; mitosis; Oncology; Onkologi; Oncology; onkologi;

    Abstract : Investigations of DNA damage response (DDR) mechanisms in normal tissues have implications for both cancer prevention and treatments. The accumulating knowledge about protein function and molecular markers makes it possible to directly trace and interpret cellular DDR in a tissue context. READ MORE

  5. 5. Cell cycle regulation in cancer: A noncoding perspective

    Author : Mohamad Ali; Göteborgs universitet; Göteborgs universitet; Gothenburg University; []
    Keywords : MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; Long Noncoding RNA; lncRNA; Cell cycle; S phase; Mitosis; Checkpoint; Cancer; SCAT7; LY6K-AS;

    Abstract : The cell cycle progression is tightly regulated to ensure error-free cell replication. The complexity of the transcriptional machinery aids to function in a spatiotemporal pattern across different phases and genomic loci. READ MORE