Search for dissertations about: "mixed lymphocyte culture"
Showing result 1 - 5 of 9 swedish dissertations containing the words mixed lymphocyte culture.
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1. Characterisation of human fetal mesenchymal stem cells
Abstract : Mesenchymal stem cells (MSCs) are present in various tissues of fetal and adult origin. I isolated and expanded MSCs from human fetal 1st trimester livers and observed that they have a shorter cell doubling time compared to adult bone marrow-derived MSCs. READ MORE
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2. Experimental studies of human fetal liver cells : in regard to in utero hematopoietic stem cell transplantation
Abstract : Successful in utero hematopoietic stem cell transplantation represents a potential step forward in the management of patients with severe inherited hematological, metabolic and immunological disorders. Animal data from a number of species have demonstrated evidence of engraftment, but to date the only effective in utero transplantations (IUTx) in humans have been performed in fetuses with severe immunodeficiencies, suggesting that the fetal immune system play a vital role in the success or failure of in utero transplantation. READ MORE
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3. Immune modulation by mesenchymal stem cells
Abstract : Mesenchymal stem cells (MSCs) were discovered as adherent cells in the bone marrow stroma that could form bone and stimulate hematopoiesis. Later, MSCs were shown to be hypoimmunogenic and to suppress proliferation of activated T cells. READ MORE
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4. Mechanisms of immune escape in EBV associated malignancies : Hodgkin's disease and Burkitt's lymphoma
Abstract : The work presented in this thesis is focused on the analysis of the mechanisms operating in the immune escape of two Epstein-Barr virus (EBV) associated tumors: Hodgkin's Disease (HD) and Burkitt's lymphoma (BL). EBV positive HD tumor cells express at least 3 viral proteins: the EBV nuclear antigen (EBNA)1, the latent membrane proteins (LMP)1 and LMP2A. READ MORE
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5. Immune Changes in Pregnancy : A Survey of some Immunological Variables in Normal and Complicated Pregnancies
Abstract : The maternal systemic immune response during pregnancy is only fragmentarily understood. An adequate immune response to the gestational product is of vital importance for a successful pregnancy. READ MORE