Search for dissertations about: "mls"
Showing result 1 - 5 of 26 swedish dissertations containing the word mls.
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1. Liposarcomas - proliferation, senescence and the role of DDIT3
Abstract : Lipomatous tumors comprise benign and malignant forms called lipomas and liposarcomas. Myxoid/round cell liposarcoma (MLS/RCLS) is the second most common liposarcoma and is characterized by the fusion oncogenes FUS-DDIT3 or EWSR1-DDIT3. READ MORE
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2. Environmental management systems : policy implementation and environmental effects
Abstract : Corporate environmental management is becoming less driven by regulatory compliance and more driven by corporate strategy. In order to gain competitive advantage, systematically assure regulatory compliance and develop more efficient operations an increasing number of organisation adopt the environmental management system (EMS) tool. READ MORE
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3. Molecular studies of genetic changes in myxoid and round cell liposarcoma
Abstract : Chromosomal translocations commonly result in the production of fusion genes and the fusion genes are often tumor-type specific. In myxoid and round cell liposarcomas (MLS/RCLS), almost 95% of the cases carry a t(12;16)(q13;p11). In the remaining 5% of the MLS/RCLS tumors, another translocation and fusion gene can be found, i.e. READ MORE
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4. The role of fusion oncogenes and cancer stem cells in myxoid liposarcoma
Abstract : Myxoid liposarcoma (MLS) is characterised by the FUS-DDIT3, or the less common EWSR1-DDIT3 fusion oncogene and is the second most common type of liposarcoma. The fusion oncogenes encode chimeric transcription factors that are causal factors in tumourigenesis however, their functions are poorly known. READ MORE
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5. Clinical and molecular studies of liposarcoma
Abstract : Aims: (1) To analyse clinicopathological characteristics, treatment and outcome of liposarcoma, and to determine whether, and how, the Scandinavian Sarcoma Group (SSG) treatment guidelines were followed; (2) to analyse tumour volume and morphology response after radiotherapy in myxoid/round cell liposarcoma (MLS/RCLS); (3) to examine the role of the MLS-specific fusion gene FUS-DDIT3 in development of liposarcomas; and (4) to analyse expression patterns of cell cycle regulating proteins in MLS. Methods: (1) A total of 319 liposarcomas reported between 1986?1998 to the SSG Register were reviewed. READ MORE