Search for dissertations about: "modelling malaria"

Showing result 1 - 5 of 11 swedish dissertations containing the words modelling malaria.

  2. 1. Modelling and Simulation to Improve Antimalarial Therapy

    Author : Jesmin Permala Lohy Das; Mats Karlsson; Martin Bergstrand; Joel Tarning; Mads Krielgaard; Uppsala universitet; []
    Keywords : MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; pharmacometrics; pharmacokinetics; pharmacodynamics; malaria; artemisinin; weekly dosing; resistant; pregnant populations; intermittent preventive therapy; parasite clearance; day 3 positivity; nomogram; Pharmacokinetics and Drug Therapy; Farmakokinetik och läkemedelsterapi; Pharmacokinetics and Drug Therapy; Farmakokinetik och läkemedelsterapi;

    Abstract : The introduction of artemisinin-based combination therapy (ACT) substantially reduced malaria-related mortality and morbidity during the past decade. Despite the widespread use of ACT, there is still a considerable knowledge gap with regards to safety, efficacy and pharmacokinetic properties of these drugs, particularly in vulnerable populations like children and pregnant women. READ MORE

  4. 2. Towards Climate Based Early Warning and Response Systems for Malaria

    Author : Maquins Odhiambo Sewe; Joacim Rocklöv; Clas Ahlm; Yesim Tozan; Madeleine Thomson; Umeå universitet; []
    Keywords : MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; Malaria; Mosquito; Lead time; Early Warnings; Forecasts; Economic Evaluation; Rainfall; KEMRI CDC HDSS; Kenya; Temperature; LST; NDVI; Climate; HDSS; GAM; GAMBOOST; DLNM; Remote Sensing; Net Benefit; Cost-Effectiveness; Boosting Regression; Weather; Public Health; Infectious Diseases; folkhälsa; Public health; Epidemiology; epidemiologi;

    Abstract : Background: Great strides have been made in combating malaria, however, the indicators in sub Saharan Africa still do not show promise for elimination in the near future as malaria infections still result in high morbidity and mortality among children. The abundance of the malaria-transmitting mosquito vectors in these regions are driven by climate suitability. READ MORE

  5. 3. Bayesian Analysis of Two Malaria Treatments and Probability Modelling of Malaria Parasite Genotypes

    Author : Cletus Kwa Kum; Stockholms universitet; []
    Keywords : NATURVETENSKAP; NATURAL SCIENCES;

    Abstract : .... READ MORE

  6. 4. Bayesian Analysis of Two Malaria Treatments and Probability Modelling of Malaria Parasite Gentypes

    Author : Cletus Kwa Kum; Daniel Thorburn; Gebrenegus Ghilagaber; Stockholms universitet; []
    Keywords : NATURVETENSKAP; NATURAL SCIENCES;

    Abstract : .... READ MORE

  7. 5. Pharmacokinetic drug-drug interactions in the management of malaria, HIV and tuberculosis

    Author : Doaa Elsherbiny; Ulrika Simonsson; Mats Karlsson; Lars Ståhle; Uppsala universitet; []
    Keywords : Pharmacokinetics Pharmacotherapy; Pharmacokinetics; Drug-drug interactions; Cytochrome P-450; Artemisinin antimalarials; Nevirapine; Lopinavir; Rifampicin; NONMEM; Farmakokinetik Farmakoterapi;

    Abstract : Malaria, Human Immunodeficiency Virus (HIV) and tuberculosis (TB) are global health problems having their worst situation in sub-Saharan Africa. Consequently, concomitant use of antimalarial, antiretroviral and antitubercular drugs may be needed, resulting in a potential risk of drug-drug interactions. READ MORE