Search for dissertations about: "molecular diagnostics"

Showing result 6 - 10 of 260 swedish dissertations containing the words molecular diagnostics.

  2. 6. Nucleic Acid Based Pathogen Diagnostics

    Author : Michael S. Akhras; Pål Nyrén; Nader Pourmand; Mats Nilsson; KTH; []
    Keywords : NATURVETENSKAP; NATURAL SCIENCES; pathogen diagnostics; antibiotic resistance; connector inversion probes CIPer ; human papillomavirus HPV ; genotyping; global health diagnostic forum; molecular inversion probe MIP ; neisseria gonorrhoeae; padlock probes; pyrosequencing; Biochemistry; Biokemi;

    Abstract : Pathogenic organisms are transmitted to the host organism through all possible connected pathways, and cause a myriad of diseases states. Commonly occurring curable infectious diseases still impose the greatest health impacts on a worldwide perspective. READ MORE

  4. 7. Improved Techniques for High-Throughput Molecular Diagnostics

    Author : Mario Curcio; KTH; []
    Keywords : DNA; Molecular Diagnostics;

    Abstract : The amount of information derived from sequencing the humangenome is leading to an exponential increase in the rate atwhich genes and genetic disorders are mapped and characterized.As a consequence, the demand for genetic testing is alsodramatically increasing. READ MORE

  5. 8. New Molecular Approaches to Glioblastoma Therapy

    Author : Sathishkumar Baskaran; Sven Nelander; Karin Forsberg Nilsson; Silvia Marino; Uppsala universitet; []
    Keywords : MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; Glioblastoma; GBM; ZBTB16; PLZF; Heterogeneity; Proteasome inhibitors; Bortezomib; Pterostilbene; drug combinations; Oncology; Onkologi; Biological Research on Drug Dependence; Biologisk beroendeforskning; Biology with specialization in Molecular Biology; Biologi med inriktning mot molekylärbiologi; Biomedical Laboratory Science; Biomedicinsk laboratorievetenskap; Medicinsk vetenskap; Medical Science; Molekylär medicin; Molecular Medicine;

    Abstract : Glioblastoma (GBM) is the most common high-grade brain tumor diagnosed in patients who are more than 50 years of age. The standard of care treatment is surgery, followed by radiotherapy and chemotherapy. The median life expectancy of patients is only between 12 to 15 months after receiving current treatment regimes. READ MORE

  6. 9. Padlock Probe-Based Assays for Molecular Diagnostics

    Author : Anja Mezger; Mats Nilsson; Paul Blainey; Stockholms universitet; []
    Keywords : NATURVETENSKAP; NATURAL SCIENCES; Padlock probes; rolling circle amplification; molecular diagnostics; in situ mutation detection; Biochemistry; biokemi;

    Abstract : Treatment success often depends on the availability of accurate and reliable diagnostic assays to guide clinical practitioners in their treatment choices. An optimal test must excel in specificity and sensitivity, and depending on the application area time, low-cost and simplicity are equally important. READ MORE

  7. 10. Towards Myosin Powered Lab-on-a-Chip Devices

    Author : Lasse ten Siethoff; Alf Månsson; Miklos Kellermayer; Linnéuniversitetet; []
    Keywords : NATURVETENSKAP; NATURAL SCIENCES; myosin; actin; molecular motors; lab-on-a-chip; nanobiotechnology; bionanotechnology; diagnostics; nanowires; nanowire arrays; Biomedical Sciences; Biomedicinsk vetenskap;

    Abstract : Myosins are protein motors that use chemical energy in the form of adenosinetriphosphate to produce force and motion. These molecular motors might be usedto power transportation in Lab-on-a-chip devices where a series of laboratory tasks(e.g. separation, concentration and detection) are performed in one sequence on asmall chip. READ MORE