Search for dissertations about: "molecular marker comparison"

Showing result 1 - 5 of 14 swedish dissertations containing the words molecular marker comparison.

  2. 1. Oxidized nucleotides as a predictor of radiation sensitivity

    Author : Ali Pour Khavari; Siamak Haghdoost; Marie Öhman; Anders Nilsson; Bo Stenerlöw; Neus Visa; Stockholms universitet; []
    Keywords : NATURVETENSKAP; NATURAL SCIENCES; NATURVETENSKAP; NATURAL SCIENCES; 8-oxo-dG; Radiation; Sensitivity; Oxidized; Nucleotides; ROS; NOS; molekylär biovetenskap; Molecular Bioscience;

    Abstract : The direct and indirect effects of IR can lead to DNA damage and activation of DNA repair. The indirect effects of ionizing radiation mediated by reactive oxygen species (ROS) which produced through radiolysis of water and if not taken care of by the antioxidant system, can also give rise to oxidative stress. READ MORE

  4. 2. Using Minisequencing Technology for Analysing Genetic Variation in DNA and RNA

    Author : Mona Fredriksson; Ann-Christine Syvänen; Aarno Palotie; Uppsala universitet; []
    Keywords : MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; Molecular medicine; microarray; minisequencing; molecular medicine; single nucleotide polymorphism; stem cell transplantation; whole genome amplification; allelic imbalance; alternative splicing; Molekylärmedicin; Molecular medicine genetics and pathology ; Molekylär medicin genetik och patologi ;

    Abstract : In this thesis, the four-color fluorescence tag-microarray minisequencing system pioneered by our group was further developed and applied for analysing genetic variation in human DNA and RNA. A SNP marker panel representing different chromosomal regions was established and used for identification of informative SNP markers for monitoring chimerism after stem cell transplantation (SCT). READ MORE

  5. 3. Disentangling small genetic differences in large Atlantic herring populations: comparing genetic markers and statistical power

    Author : Lena C. Larsson; Linda Laikre; Nils Ryman; Lorenz Hauser; Stockholms universitet; []
    Keywords : NATURVETENSKAP; NATURAL SCIENCES; conservation genetics; marine fish; spatial and temporal genetic variation; molecular marker comparison; allozyme; microsatellite; selection; fisheries management; Biology; Biologi; populationsgenetik; Population Genetics;

    Abstract : Genes are the foundation of evolution and biodiversity. The genetic structure of natural populations needs to be understood to maintain exploited resources rationally. This thesis focuses on genetic variability and methods to determine spatial and temporal genetic heterogeneities. READ MORE

  6. 4. Biochemical and functional properties of mammalian bone alkaline phosphatase isoforms during osteogenesis

    Author : Cecilia Halling Linder; Per Magnusson; Elvar Theodorsson; Göran Andersson; Torgny Stigbrand; Linköpings universitet; []
    Keywords : MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES;

    Abstract : The human skeleton is a living and dynamic tissue that constantly is being renewed in a process called bone remodeling. Old bone is resorbed by osteoclasts and new bone is formed by osteoblasts. READ MORE

  7. 5. Single-cell RNA sequencing provides novel insights into spider development and represents an innovative alternative to study the evolution and development of panarthropods

    Author : Brenda Irene Medina-Jiménez; Ralf Janssen; Graham Budd; Angelika Stollewerk; Uppsala universitet; []
    Keywords : NATURVETENSKAP; NATURAL SCIENCES; panarthropod; spider embryo; single-cell RNA sequencing; EvoDevo; candidate gene approach; gene expression; cluster marker; Biology with specialization in Molecular Biology; Biologi med inriktning mot molekylärbiologi; Earth Science with specialization in Historical Geology and Palaeontology; Geovetenskap med inriktning mot historisk geologi och paleontologi;

    Abstract : Panarthropoda is a monophyletic group of invertebrate animals with a segmented body, paired appendages, dorsal brain, and ventral nerve cords. In order to study the mechanisms underpining their evolution, I study the genetic factors that drive their development. READ MORE