Search for dissertations about: "molecular switch"

Showing result 1 - 5 of 162 swedish dissertations containing the words molecular switch.

  1. 1. Meticulous control of the T3SS of Yersinia is essential for full virulence

    Author : Ann-Catrin Björnfot; Hans Wolf-Watz; Kelly T. Hughes; Umeå universitet; []
    Keywords : NATURVETENSKAP; NATURAL SCIENCES; Yersinia; type III secretion; YscU; substrate specificity switch; heat shock proteins; VagH; methyltransferase; virulence; Molecular biology; Molekylärbiologi; molekylärbiologi; Molecular Biology;

    Abstract : The type III secretion system (T3SS) of pathogenic Yersinia pseudotuberculosis is involved in virulence. The syringe-like secretion system spans both bacterial membranes and is responsible for the ability of Yersinia to transfer toxic proteins (Yop proteins) into the eukaryotic target cell. READ MORE

  2. 2. Poly(A)-Specific Ribonuclease (PARN)

    Author : Yan-Guo Ren; Eric Westhof; Uppsala universitet; []
    Keywords : NATURVETENSKAP; NATURAL SCIENCES; Cell and molecular biology; Poly A -specific ribonuclease; PARN; deadenylation; processive; oligomeric; cap interacting; aminoglycoside; active site; FE2 -mediated cleavage; metal ion switch; Cell- och molekylärbiologi; Cell and molecular biology; Cell- och molekylärbiologi; Molekylär cellbiologi; Molecular Cellbiology;

    Abstract : Degradation of the mRNA 3'-end located poly(A) tail is an important step for mRNA decay in mammalian cells. Thus, to understand mRNA decay in detail, it is important to identify the catalytic activities involved in degrading poly(A). READ MORE

  3. 3. Molecular and functional anatomy of the mouse olfactory epithelium

    Author : Viktoria Vedin; Anna Berghard; Urban Lendahl; Umeå universitet; []
    Keywords : NATURVETENSKAP; NATURAL SCIENCES; olfactory epithelium; odorant receptor; zone; odorant; gene expression; cell specification; c-Fos; dichlobenil; olfactometry; proliferation; Molecular biology; Molekylärbiologi;

    Abstract : The olfactory system is important for social behaviors, feeding and avoiding predators. Detection of odorous molecules is made by odorant receptors on specialized sensory neurons in the olfactory epithelial sheet. READ MORE

  4. 4. Molecular properties of disordered plant dehydrins : Membrane interaction and function in stress

    Author : Sylvia Eriksson; Pia Harryson; Steffen Graether; Stockholms universitet; []
    Keywords : NATURVETENSKAP; NATURAL SCIENCES; abiotic stress; dehydrin; intrinsically disordered proteins; Lea-proteins; phospholipids; Biochemistry; biokemi;

    Abstract : Dehydrins are intrinsically disordered plant stress-proteins. Repetitively in their sequence are some highly conserved stretches of 7-17 residues, the so called K-, S-, Y- and lysine rich segments. READ MORE

  5. 5. Control of Quasi-Equivalence in Virus Capsids

    Author : Charlotte Helgstrand; B. V. Venkataram Prasad; Uppsala universitet; []
    Keywords : NATURVETENSKAP; NATURAL SCIENCES; Cell and molecular biology; crystallography; bacteriophage; virus; RNA; capsid; quasi-equivalence; assembly; Cell- och molekylärbiologi; Cell and molecular biology; Cell- och molekylärbiologi; Molecular Biotechnology; Molekylär bioteknik;

    Abstract : Many T=3 plant and insect viruses use a molecular switch in form of order/disorder of a segment of the polypeptide chain to regulate the quasi-equivalent contacts. The structure of a mutant of the T=3 capsid of bacteriophage fr confirms that this virus and other members of the Leviviridae family lack a switch mechanism. READ MORE