Search for dissertations about: "molecules"
Showing result 16 - 20 of 3500 swedish dissertations containing the word molecules.
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16. Generation and characterization of Affibody molecules targeting HER3
Abstract : In the field of oncology, the ability to target specific tumor cells using highly selective targeting molecules is an attractive and emerging concept. In this context, the epidermal growth factor receptor HER3 has proven central to the biology behind many different human cancers and inhibition of the signaling mediated by this receptor could provide antitumoral effects. READ MORE
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17. Diffusion of large molecules in steam-exploded wood
Abstract : The diffusion of large molecules in wood pre-treated with steam explosion is important to understand in the context of the materials biorefinery. Steam explosion is a pretreatment method used to both open up the internal structure of wood and increase the accessibility of the cell walls of the wood with the use of high-pressure steam, and it is considered an energy-efficient method. READ MORE
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18. Affibody Molecules for HER3-targeted Theranostics of Malignant Tumours
Abstract : The HER3 receptor plays a strong role in disease progression and resistance to therapies in several cancer types. Due to its endogenous expression and low overexpression in malignant tumours, it is a particularly challenging target. READ MORE
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19. Radiolabelled affibody molecules for imaging EGFR expression in tumours
Abstract : Affibody molecules are promising scaffold-based targeting proteins for radionuclide imaging and cancer therapy. This thesis is based on 5 original research articles (Papers I-V), with the primary focus being placed on the optimization of molecular design of EGFR-binding affibody variants for high contrast imaging of epidermal growth factor receptor (EGFR) expression in tumours. READ MORE
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20. Detection and Sequencing of Amplified Single Molecules
Abstract : Improved analytical methods provide new opportunities for both biological research and medical applications. This thesis describes several novel molecular techniques for nucleic acid and protein analysis based on detection or sequencing of amplified single molecules (ASMs). READ MORE