Search for dissertations about: "molekylär biovetenskap"

Showing result 1 - 5 of 98 swedish dissertations containing the words molekylär biovetenskap.

  1. 1. In vitro and in vivo aspects of intrinsic radiosensitivity

    University dissertation from Stockholm : Department of Molecular Biosciences, the Wenner-Gren Institute

    Author : Karl Brehwens; Stockholms universitet.; [2014]
    Keywords : NATURVETENSKAP; NATURAL SCIENCES; Radiation biology; changing dose rates; cytogenetics; hypothermia; X-rays; radiotherapy; osteoradionecrosis; biomarkers; oxidative stress; individual radiosensitivity; molekylär biovetenskap; Molecular Biosciences;

    Abstract : This thesis focuses on how physical and biological factors influence the outcome of exposures to γ/X-rays. That the dose rate changes during real life exposure scenarios is well-known, but radiobiological data from exposures performed at increasing or decreasing dose rates is lacking. READ MORE

  2. 2. Pathogenic Neisseria : Single cell motility, multicellular dynamics and antimicrobial susceptibility

    University dissertation from Stockholm : Wenner-Grens institut, Department of Molecular Biosciences, The Wenner-Gren Institute, Stockholm University

    Author : Olaspers Sara Eriksson; Stockholms universitet.; [2014]
    Keywords : NATURVETENSKAP; NATURAL SCIENCES; Neisseria; Type IV pili; Twitching motility; PilT; Microcolony dynamics; PilU; NafA; Antimicrobial peptide; Cell-penetrating peptide; molekylär biovetenskap; Molecular Bioscience;

    Abstract : Neisseria meningitidis and Neisseria gonorrhoeae can colonize humans without causing any symptoms. However, gonorrhea and invasive meningococcal disease are serious health concerns. An essential virulence factor for neisserial adhesion to host cells, twitching motility and microcolony formation/aggregation is the retractile type IV pili (Tfp). READ MORE

  3. 3. The ADAR editing enzymes as therapeutic targets

    University dissertation from Stockholm : Department of Molecular Biosciences, The Wenner-Gren Institute, Stockholm University

    Author : Kajsa Fritzell; Stockholms universitet.; [2018]
    Keywords : NATURVETENSKAP; NATURAL SCIENCES; molekylär biovetenskap; Molecular Bioscience;

    Abstract : Editing by deamination of adenosine to inosine (A-to-I) in double-stranded RNA is a common event in the human transcriptome. Altered levels of the essential ADAR1 activity are associated with disease. Children with mutations in the ADAR1 gene suffer from fatal Aicardi-Goutières syndrome (AGS) characterized by aberrant interferon expression. READ MORE

  4. 4. Antimicrobial peptides and virulence factors in meningococcal colonisation and disease

    University dissertation from Stockholm : Department of Molecular Biosciences, The Wenner-Gren Institute, Stockholm University

    Author : Miriam Geörg; Stockholms universitet.; [2014]
    Keywords : NATURVETENSKAP; NATURAL SCIENCES; Neisseria meningitidis; antimicrobial peptide; LL-37; cell-penetrating peptide; resistance; polynucleotide phosphorylase; molekylär biovetenskap; Molecular Bioscience;

    Abstract : The Gram-negative bacterium Neisseria meningitidis is a transient commensal of the human nasopharynx, but occasionally causes life-threatening disease. During colonisation of its niche, N. meningitidis has to overcome innate immune defences, including the expression of antimicrobial peptides (AMPs). READ MORE

  5. 5. Low Protein Diets and Their Effects on Brown Adipose Tissue

    University dissertation from Stockholm : Stockholm University

    Author : Erik Lindsund; Stockholms universitet.; [2019]
    Keywords : NATURVETENSKAP; NATURAL SCIENCES; Obesity; Protein diets; Dietary protein; Brown adipose tissue; Brown fat; BAT; UCP10; Uncoupeling protein 1; molekylär biovetenskap; Molecular Bioscience; Physiology; fysiologi;

    Abstract : Obesity is a rising health issue and has been linked with a relative decrease of dietary protein, which promotes higher food intake. Brown adipose tissue is a heat-producing, energy-wasting organ that has been shown to be enhanced by a low protein diet. However, the mechanism of how this occurs is largely unknown. READ MORE