Search for dissertations about: "molekylär biovetenskap"

Showing result 1 - 5 of 170 swedish dissertations containing the words molekylär biovetenskap.

2. 1. Tracking single molecules in uncharted territory : A single-molecule method to study kinetics in live bacteria

   Author : Javier Aguirre Rivera; Magnus Johansson; Dmitri N. Ermolenko; Uppsala universitet; []
   Keywords : NATURAL SCIENCES; NATURVETENSKAP; NATURVETENSKAP; NATURAL SCIENCES; single-molecule; protein synthesis; fluorescence microscopy; antibiotics; aminoglycosides; macrolides; apramycin; gentamicin; paromomycin; S13; translation; bacteria; Molekylär biovetenskap; Molecular Life Sciences;

   Abstract : The synthesis of proteins, also known as translation, is a fundamental process in every living organism. The steps in the translation of genetic information to functional proteins have been meticulously studied, mostly using in vitro techniques, yielding a detailed model of their mechanisms. READ MORE

4. 2. The role of non-coding single-stranded oligonucleotides on Respiratory syncytial virus infection

   Author : Sandra Axberg Pålsson; Anna-Lena Spetz; Annika Karlsson; Stockholms universitet; []
   Keywords : NATURAL SCIENCES; NATURVETENSKAP; Respiratory syncytial virus RSV ; single-stranded oligonucleotide ssON ; small non-coding RNA sncRNA ; nucleolin; virus infection; antiviral; molekylär biovetenskap; Molecular Bioscience;

   Abstract : Respiratory syncytial virus (RSV) is an enveloped RNA virus of the Pneumoviridae family. RSV is reported to infect host cells by receptor-mediated endocytosis, also called clathrin-dependent endocytosis. Many reports indicate that the virus utilizes the host receptor nucleolin for entry. READ MORE

5. 3. Guardians of the genome : Connecting chromatin structure and genome integrity in Saccharomyces cerevisiae

   Author : Stefanie Lena Bauer; Stefan U. Åström; Brian Luke; Stockholms universitet; []
   Keywords : NATURAL SCIENCES; NATURVETENSKAP; molekylär biovetenskap; Molecular Bioscience;

   Abstract : Branched DNA structures arise during recombination and during other DNA repair processes such as repair of stalled replication forks. One branched structure, the Holliday Junction (HJ), is a four-way junction that can connect sister chromatids or homologous chromosomes. We show a physical interaction between the HJ-cleaving enzyme Yen1 and Uls1. READ MORE

6. 4. The impact of cytochrome P4501-inhibitors on aryl hydrocarbon receptor signaling

   Author : Johanna Bengtsson; Emma Wincent; Ulf Rannug; Malin Celander; Stockholms universitet; []
   Keywords : MEDICAL AND HEALTH SCIENCES; MEDICIN OCH HÄLSOVETENSKAP; MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; molekylär biovetenskap; Molecular Bioscience;

   Abstract : The aryl hydrocarbon receptor (AHR) best known as a ligand-activated transcription factor that mediates toxic responses to xenobiotics such as dioxins, is also activated by certain endogenous compounds. Activation of the AHR up-regulates transcription of a large number of genes, including those encoding members of the cytochrome P450 1 family of enzymes (CYP1s). READ MORE

7. 5. Immune maturation and lymphocyte characteristics in relation to early gut bacteria exposure

   Author : Sophia Björkander; Eva Sverremark Ekström; Hanne Frøkiær; Stockholms universitet; []
   Keywords : NATURAL SCIENCES; NATURVETENSKAP; NATURVETENSKAP; NATURAL SCIENCES; Allergy; cell-free supernatant; chemokines; colonization; cytokines; FOXP3; immune-maturation; lactobacilli; lymphocytes; NK-cells; Staphylococcus aureus; unconventional T-cells; molekylär biovetenskap; Molecular Bioscience;

   Abstract : At birth, the immune system is immature and the gut microbiota influences immune maturation. Staphylococcus aureus (S. aureus) and lactobacilli are part of the neonatal gut microbiota and have seemingly opposite effects on the immune system. S. READ MORE