Search for dissertations about: "molekylärbiologi ,umeå"

Showing result 11 - 15 of 350 swedish dissertations containing the words molekylärbiologi ,umeå.

  2. 11. Streptococcal immunoglobulin degrading enzymes of the IdeS and IgdE family

    Author : Christian Spoerry; Ulrich von Pawel-Rammingen; Heiko Herwald; Umeå universitet; []
    Keywords : MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; NATURVETENSKAP; NATURAL SCIENCES; Streptococcus; S. pyogenes; S. agalactiae; S. suis; S. porcinus; S. pseudoporcinus; S. equi subsp. zooepidemicus; protease; immunoglobulin; immune evasion; IdeS; IgdE; molekylärbiologi; Molecular Biology;

    Abstract : Bacteria of the genus Streptococcus are common asymptomatic colonisers of humans and animals. As opportunistic pathogens they can however, depending on their host’s immune status and other circumstances, cause mild to very severe infections. READ MORE

  4. 12. Functional aspects of wobble uridine modifications in yeast tRNA

    Author : Anders Esberg; Anders Byström; James T. Anderson; Umeå universitet; []
    Keywords : NATURVETENSKAP; NATURAL SCIENCES; Molecular biology; Transfer RNA; Modified nucleosides; Elongator complex; Translation; Kluyveromyces lactis γ-toxin; Molekylärbiologi; molekylärbiologi; Molecular Biology;

    Abstract : Transfer RNAs (tRNA) function as adaptor molecules in the translation of mRNA into protein. These adaptor molecules require modifications of a subset of their nucleosides for optimal function. The most frequently modified nucleoside in tRNA is position 34 (wobble position), and especially uridines present at this position. READ MORE

  5. 13. Antiphagocytosis by Yersinia pseudotuberculosis : role of the YopH target proteins

    Author : Ming Yuan; Maria Fallman; Tommy Nilsson; Umeå universitet; []
    Keywords : MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; Molecular biology; Cas; Fyb; mAbp1; SKAP-HOM; Yersinia pseudotuberculosis; YopH; Molekylärbiologi; molekylärbiologi; Molecular Biology;

    Abstract : The enteropathogenic bacterium Yersinia pseudotuberculosis binds to β1 integrins on a host cell via its surface protein invasin. This event stimulates signal transduction to the actin cytoskeleton of the eukaryotic cell, which allows the cell to engulf the bacterium that is attached to its surface. However, the pathogen Y. READ MORE

  6. 14. Peptidoglycan recognition proteins in Drosophila melanogaster

    Author : Thomas Werner; Dan Hultmark; Bruno Lemaitre; Umeå universitet; []
    Keywords : NATURVETENSKAP; NATURAL SCIENCES; Molecular biology; Drosophila; PGRP; peptidoglycan; pattern recognition; imd; Relish; isoform; RNAi; mbn-2; Molekylärbiologi; Molecular biology; Molekylärbiologi; molekylärbiologi; Molecular Biology;

    Abstract : The fruit fly Drosophila melanogaster is an excellent model organism to study the innate immune response, because insects and mammals share conserved features regarding the recognition and destruction of microorganisms and Drosophila is easily accessible to genetic manipulation. In my present study, I identified a new family of pattern recognition molecules for bacterial peptidoglycan in Drosophila, the Peptidoglycan Recognition Proteins (PGRP). READ MORE

  7. 15. Type III secretion- the various functions of the translocon operon in bacterial pathogenesis

    Author : Jeanette E Bröms; Åke Forsberg; Michael Koomey; Umeå universitet; []
    Keywords : NATURVETENSKAP; NATURAL SCIENCES; Molecular biology; Yersinia; Pseudomonas aeruginosa; type III secretion; chaperone; translocation; regulation; lcrGVHyopBD; pcrGVHpopBD; Molekylärbiologi; Molecular biology; Molekylärbiologi; molekylärbiologi; Molecular Biology;

    Abstract : In order to establish colonisation of a human host, pathogenic Yersinia use a type III protein secretion system to directly intoxicate host immune cells. Activation of this system requires target cell contact and is a highly regulated process. READ MORE