Search for dissertations about: "molekylärbiologi ,umeå"
Showing result 16 - 20 of 346 swedish dissertations containing the words molekylärbiologi ,umeå.
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16. Meticulous control of the T3SS of Yersinia is essential for full virulence
Abstract : The type III secretion system (T3SS) of pathogenic Yersinia pseudotuberculosis is involved in virulence. The syringe-like secretion system spans both bacterial membranes and is responsible for the ability of Yersinia to transfer toxic proteins (Yop proteins) into the eukaryotic target cell. READ MORE
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17. Function of wobble nucleoside modifications in tRNAs of Salmonella enterica Serovar Typhimurium
Abstract : Transfer RNA from all organisms has modified nucleosides and position 34 (the wobble position) is one of the most extensively modified positions. Some wobble nucleoside modifications restrict codon choice (e.g. 5-methylaminomethyl-2-thiouridine, mnm5s2U) while some extend the decoding capacity (e. READ MORE
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18. Identification of new virulence factors in Francisella tularensis
Abstract : Francisella tularensis, the causative agent of tularemia, is a highly virulent bacterium with an infection dose of less than ten bacteria. The ability of a pathogen to cause infection relies on different virulence mechanisms, but in Francisella tularensis relatively few virulence factors are known. Two F. READ MORE
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19. Effects of invasin and YopH of Yersinia pseudotuberculosis on host cell signaling
Abstract : Integrins are a large family of membrane-spanning heterodimeric (αβ) receptors that bind to ligands on other cells or to extracellular matrix (ECM) proteins. These receptors mediate bidirectional signaling over the cell membrane to induce signaling cascades mediating functions as cell adhesion, spreading and migration. READ MORE
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20. On the role of small regulatory molecules in the interplay between σ54- and σ70-dependent transcription
Abstract : Signal responsive transcriptional control in bacteria is mediated through both specific and global regulatory circuits to attune promoter output to prevailing conditions. Divergent transcription of a regulatory gene and a cognate promoter under its control provides an opportunity for interplay between transcription dependent on RNA polymerases utilizing various σ-factors, each of which programs the holoenzyme to recognize different classes of promoters. READ MORE