Search for dissertations about: "monocyte HLA-DR"
Found 5 swedish dissertations containing the words monocyte HLA-DR.
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1. Dynamics of Human Leukocyte Antigen-D Related expression in bacteremic sepsis
Abstract : Monocytic human leukocyte antigen-D related (mHLA-DR) expression determined by flow cytometry has been suggested as a biomarker of sepsisinduced immunosuppression.In order to facilitate use of HLA-DR in clinical practice, a quantitative real-time PCR technique measuring HLA-DR at the transcription level was developed and evalutated. READ MORE
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2. Tumor-mediated changes in the immune system of cancer patients : a balancing act between suppressors and effectors
Abstract : Tumors and immune cells interact in many ways: immune cells can recognize and even kill tumor cells, while the tumor on the other hand can induce cells of the immune system to participate in tumor-mediated immune subversion. We studied immunosuppressive effects that human tumors exert on immune effector cells, particularly T cells, by inducing suppressive myeloid cells and decreasing T cell functional capacity. READ MORE
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3. The inflammatory response in extravasated leukocytes in patients with coronary artery disease
Abstract : Coronary artery disease (CAD) is a manifestation of a chronic inflammation in the coronary arteries. The inflammatory process results in accumulation of monocyte derived cells and formation of atherosclerotic plaques in the intima of the vessel wall. READ MORE
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4. CTLA-4 expression, regulation and associations in autoimmune myasthenia gravis
Abstract : Myasthenia gravis (MG) is a neuromuscular disease with muscle weakness due to an autoimmune attack against the nicotinic acetylcholine receptor (nAChR) on the skeletal muscle endplate. Cytotoxic-T-lymphocyte-associated antigen 4 (CTLA-4) plays a global inhibitory role in the immune system and has a crucial role in autoimmunity. READ MORE
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5. Exosomes : nano-vesicles in immune regulation
Abstract : Nano-vesicles (30-100 nm) with an endosome-derived limiting membrane are called exosomes. These are released from the cell when the endosome fuses with the outer cell membrane. Exosomes from antigen presenting cells (APC) carry MHC class I and class II as well as integrins, tetraspanins and co-stimulatory molecules. READ MORE