Search for dissertations about: "morphine"

Showing result 6 - 10 of 116 swedish dissertations containing the word morphine.

2. 6. Anterior cruciate ligament injury. Results after reconstruction in terms of function, postoperative pain and kinematics

   Author : Sveinbjörn Brandsson; Göteborgs universitet; []
   Keywords : MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; Anterior cruciate ligament; reconstruction; bone-patellar tendon-bone graft; post-operative pain; morphine; pain reduction; kinematics; radiostereometric analysis; RSA.;

   Abstract : The aim of this study was to evaluate the functional and objective outcome after anterior cruciate ligament reconstruction using bone-patellar tendon-bone grafts. Other main objectives were to evaluate postoperative pain, pain reduction and knee kinematics after anterior cruciate ligament injury and reconstruction. READ MORE

4. 7. Olfactory Transfer of Analgesic Drugs After Nasal Administration

   Author : Ulrika Espefält Westin; Erik Björk; Eva Brittebo; Margareta Hammarlund-Udenaes; Paolo Colombo; Uppsala universitet; []
   Keywords : Pharmaceutics; Nasal administration; Olfactory transfer; Olfactory pathways; Central nervous system; Blood-brain barrier; Nasal respiratory mucosa; Olfactory mucosa; Olfactory bulb; Horizontal Ussing chamber; Morphine; Dihydroergotamine; Rat; Mouse; Swine; Autoradiography; Viability; Powder formulations; Galenisk farmaci;

   Abstract : Nasal administration of analgesics for achieving rapid pain relief is currently a topic of great interest. The blood-brain barrier (BBB) restricts access to the central nervous system (CNS) for several central-acting drugs, such as morphine and dihydroergotamine, which results in a substantial effect delay. READ MORE

5. 8. Neuroinflammation and pain

   Author : Linda Block; Göteborgs universitet; []
   Keywords : MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; Neuroinflammation; Pain; Persistant pain; Astrocytes; Morphine; Naloxone; Intrathecal administration;

   Abstract : ABSTRACT Background: Persistent pain that remains long after the physiological trigger has been resolved is a disabling condition. A possible mechanism for the transition from acute physiological pain to persistent pain involves low-grade inflammation in the central nervous system, in which inflammatory-activated astrocytes play a significant role. READ MORE

6. 9. Experimental and clinical studies on the antiemetic effects of propofol

   Author : Bengt Hammas; Uppsala universitet; []
   Keywords : MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; Surgery; gastric emptying; gastric tone; orocecal transit time; propofol; dopamine; serotonin; morphine; postoperative nausea and vomiting; Kirurgi; Surgery; Kirurgi; anestesiologi; Anaesthesiology;

   Abstract : Postoperative nausea and vomiting (PONV) is still a clinical problem and its incidence is unacceptably high. After the introduction of propofol as an agent for induction and maintenance of anesthesia, it was reported that the incidence of PONV was lower. It was also proposed that propofol possesses antiemetic effects. READ MORE

7. 10. Premedication for intubation in newborn infants; pain assessment, pharmacokinetics and pharmacodynamics

   Author : Elisabeth Norman; Lund Pediatrik; []
   Keywords : MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; Premedication; pain; premature; newborn; aEEG; randomized controlled trial; thiopental; morphine; remifentanil; rapid sequence induction; ibntubation; pharmacokinetics; pharmacodynamics;

   Abstract : Preterm infants undergo intensive care during a vulnerable period with hemodynamic instability and a rapidly developing and immature CNS. Adequate pain management is essential, since pain experience might lead to acute physiological reactions as well as neurological and neuropsychological sequels. READ MORE