Search for dissertations about: "morphogen"

Showing result 6 - 10 of 21 swedish dissertations containing the word morphogen.

  2. 6. Investigation of Hox gene expression and Wnt-signalling in basally branching ecdysozoans

    Author : Mattias Hogvall; Ralf Janssen; Graham Budd; Andreas Hejnol; Andrew Peel; Uppsala universitet; []
    Keywords : NATURVETENSKAP; NATURAL SCIENCES; Wnt signalling pathway; Hox genes; Fz receptors; Onychophora; Priapulida; Ecdysozoa; Biology with specialization in Evolutionary Organismal Biology; Biologi med inriktning mot evolutionär organismbiologi;

    Abstract : One of the most important processes in the development of an animal is the determination and patterning of the primary body axis, the anterior-posterior (AP) axis. After the AP axis has been established the embryo grows and elongates through posterior elongation. READ MORE

  4. 7. Resolving developing neuronal lineages in the ventral midbrain

    Author : Nigel Kee; Karolinska Institutet; Karolinska Institutet; []
    Keywords : ;

    Abstract : The numerous cells and cell types of our bodies originate from a fertilised egg. Through the study of the developing embryo, we have come to understand much about how different cells in different tissues arise from this single cell, and how they are related to one another within an expansive family tree. READ MORE

  5. 8. Design of Oligosaccharide Libraries to Characterize Heparan Sulfate – Protein Interactions

    Author : Sindhulakshmi Kurup; Dorothe Spillmann; Ulf Lindahl; Jacob Vandenborn; Uppsala universitet; []
    Keywords : Biochemistry; heparan sulfate; oligosaccharide; phage display antibodies; Biokemi;

    Abstract : Heparan sulfates (HSs) are a class of anionic carbohydrate chains found at cell surfaces and in the extracellular matrix where they interact with a number of proteins. HS is characterized by extreme structural heterogeneity, and has been implicated in a number of biological phenomenon like embryogenesis, morphogen gradient formation and signalling of growth factors such as FGF, PDGF etc. READ MORE

  6. 9. Activation and Regulation of TRPV1 : Studies in Recombinant Human Neuroblastoma TRPV1-SHSY5Y Cells

    Author : Johanna EL Andaloussi-Lilja; Anna Forsby; Antonio Ferrer-Montiel; Stockholms universitet; []
    Keywords : MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; nociception; neurotrophic factors; eye irritation; stable transfection; Ca2 ; Neurochemistry; Neurokemi; Neurochemistry and Molecular Neurobiology; neurokemi med molekylär neurobiologi;

    Abstract : TRPV1 is a transmembrane non-selective cation channel with preference for Ca2+. The receptor is primarily localised on dorsal root ganglion neurons and is activated by numerous endogenous and exogenous potentially irritating ligands eliciting pain. READ MORE

  7. 10. Glycosaminoglycan Biosynthesis in Zebrafish

    Author : Beata Filipek-Górniok; Lena Kjellén; Johan Ledin; Kay Grobe; Uppsala universitet; []
    Keywords : NATURVETENSKAP; NATURAL SCIENCES; NATURVETENSKAP; NATURAL SCIENCES; MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; Heparan sulfate; chondroitin dermatan sulfate; biosynthesis; development; N-deacetylase N-sulfotransferase; glycosyltransferases; morpholino; CRISPR-Cas9;

    Abstract : Proteoglycans (PGs) are composed of highly sulfated glycosaminoglycans chains (GAGs) attached to specific core proteins. They are present in extracellular matrices, on the cell surface and in storage granules of hematopoietic cells. READ MORE