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Showing result 1 - 5 of 23 swedish dissertations matching the above criteria.

2. 1. A Bioinformatics Study of Human Transcriptional Regulation

   Author : Adam Ameur; Jan Komorowski; Claes Wadelius; Philipp Bucher; Uppsala universitet; []
   Keywords : NATURVETENSKAP; NATURAL SCIENCES; bioinformatics; microarray; ChIP-chip; ChIP-seq; transcription factor; histone modification; motif search; Bioinformatics; Bioinformatik;

   Abstract : Regulation of transcription is a central mechanism in all living cells that now can be investigated with high-throughput technologies. Data produced from such experiments give new insights to how transcription factors (TFs) coordinate the gene transcription and thereby regulate the amounts of proteins produced. READ MORE

4. 2. Development of 18F- and 68Ga-Labelled Tracers : Design Perspectives and the Search for Faster Synthesis

   Author : Elisabeth Blom; Bengt Långström; Oleksiy Itsenko; Irina Velikyan; Farhad Karimi; Frank Rösch; Uppsala universitet; []
   Keywords : NATURVETENSKAP; NATURAL SCIENCES; PET; nucleophilic 18F-fluorination; perfluoro; F-SPE; molecular design; 68Ga; chelators; DOTA; NOTA; microwave; halogen exchange; harmine; biotin; RGD; VEGF; CRP; Chemistry; Kemi; Organisk kemi; Organic Chemistry;

   Abstract : This thesis deals with the design of 18F- and 68Ga-labelled positron emission tomography (PET) tracers and the development of technologies that enable faster and simpler preparation with high specific radioactivity. Techniques like microwave heating and reducing the concentrations of the precursor were investigated with this perspective. READ MORE

5. 3. Theoretical Investigations of Two-Dimensional Materials : Studies on Electronic, Magnetic, Mechanical, and Thermal Properties

   Author : Xin Chen; Biplab Sanyal; Susanne Mirbt; Kristian Sommer Thygsen; Uppsala universitet; []
   Keywords : NATURVETENSKAP; NATURAL SCIENCES; 2D materials; DFT; Structure search; Functional materials; Physics with spec. in Atomic; Molecular and Condensed Matter Physics; Fysik med inriktning mot atom- molekyl- och kondenserande materiens fysik;

   Abstract : Two-dimensional (2D) materials have been paid enormous attention since the first realization of graphene in 2004, in connection to high-speed flexible electronics, 2D magnetism, optoelectronics, and so on. Apart from graphene, many new 2D materials with special properties have been predicted and synthesized. READ MORE

6. 4. The genetics of antibiotic production and the role of antibiotics in biological control of Erwinia amylovora by Erwinia herbicola

   Author : Sandra A. I. Wright; Cornell University; []
   Keywords : NATURVETENSKAP; NATURAL SCIENCES; NATURVETENSKAP; NATURAL SCIENCES; Biological sciences; fire blight; pantocin; Plant pathology; Microbiology; Molecular biology; 0480:Plant pathology; 0307:Molecular biology; 0410:Microbiology;

   Abstract : Erwinia herbicola is an epiphyte of apple and pear with potential as a biocontrol agent of Erwinia amylovora, which causes fire blight. This research aimed to assess the relative role of antibiotics produced by E. herbicola, Eh318 as a mechanistic basis for biocontrol. READ MORE

7. 5. Partial methane oxidation from electronic structure calculations

   Author : Adam Arvidsson; Chalmers tekniska högskola; []
   Keywords : NATURVETENSKAP; NATURAL SCIENCES; NATURVETENSKAP; NATURAL SCIENCES; NATURVETENSKAP; NATURAL SCIENCES; TEKNIK OCH TEKNOLOGIER; ENGINEERING AND TECHNOLOGY; NATURVETENSKAP; NATURAL SCIENCES; NATURVETENSKAP; NATURAL SCIENCES; ZSM-5 zeolite; density functional theory; microkinetic modelling; Mo6S8 cluster; partial methane oxidation;

   Abstract : Investigating catalytic reactions with computational methods is a powerful approach to understand fundamental aspects of catalytic reactions and find ways to guide catalytic design. Partial methane oxidation is one example of a reaction with intriguing challenges, where a detailed atomistic approach may help to unravel the bottlenecks of this, as of yet, inefficient reaction. READ MORE