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Showing result 1 - 5 of 225 swedish dissertations matching the above criteria.
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1. The emotional motor system and gastrointestinal symptoms
Abstract : There is a significant comorbidity between anxiety/depression and functional gastrointestinal syndromes, such as irritable bowel syndrome (IBS) and functional dyspepsia. The pathophysiological link between emotions and the gut is not known. READ MORE
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2. Sensor-based knowledge- and data-driven methods : A case of Parkinson’s disease motor symptoms quantification
Abstract : The overall aim of this thesis was to develop and evaluate new knowledge- and data-driven methods for supporting treatment and providing information for better assessment of Parkinson’s disease (PD).PD is complex and progressive. There is a large amount of inter- and intravariability in motor symptoms of patients with PD (PwPD). READ MORE
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3. Dopaminergic stabilizers for the treatment of schizophrenia. Rat studies focusing on negative symptoms and mechanisms of action
Abstract : Schizophrenia is a severe mental disorder manifested by positive, negative and cognitive symptoms. Current antipsychotic drugs have poor effects on negative and cognitive symptoms, thus necessitating the development of new antipsychotic treatments. Dopaminergic stabilizers constitute a novel concept for the treatment of schizophrenia. READ MORE
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4. Non-motor symptoms in Parkinson’s disease : modeling and mechanisms
Abstract : Parkinson’s disease (PD) is a common neurodegenerative disorder, typically characterized by the progressive death of midbrain dopaminergic neurons projecting from the substantia nigra to other areas within the basal ganglia. Historically, PD has been diagnosed as a purely motor disorder dominated by bradykinesia (slowness of movement), rigidity, resting tremor, and postural instability. READ MORE
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5. Gastrointestinal symptoms in chronic renal failure. Prevalence and pathophysiological mechanisms
Abstract : Chronic renal failure (CRF) has a varying etiology and is characterised by an increasing accumulation of toxic metabolic waste products in the blood. Malnutrition is a common finding in uraemic patients and is regarded as a marker for morbidity and mortality. Many factors, including gastrointestinal (GI) symptoms, lead to malnutrition in CRF. READ MORE