Search for dissertations about: "mouse brain"

Showing result 1 - 5 of 461 swedish dissertations containing the words mouse brain.

  2. 1. Brain Regeneration - in vitro and in vivo studies of exercise-related effects on brain plasticity

    Author : Cecilia Bull; Göteborgs universitet; []
    Keywords : brain; neural progenitor cells; stem cells; hippocampus; corpus collosum; rat; mouse; regeneration; neurogenesis; oligodendrogenesis; irradiation; exercise;

    Abstract : Neural stem and progenitor cells in the germinal regions of the adult brain, such as the hippocampus, are of great interest, because they provide the possibility for enhanced brain plasticity or can contribute to endogenous cell replacement after injury or disease. Voluntary exercise was recently shown to robustly induce cellular and structural plasticity, thereby contributing to overall brain health. READ MORE

  4. 2. Temporal dynamics of brain plasticity : characterizing brain structural changes during skill acquisition

    Author : Tomás Mediavilla; Daniel Marcellino; Alexandra Badea; Umeå universitet; []
    Keywords : MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; Motor learning; brain plasticity; structural plasticity; magnetic resonance imaging; voxel-based morphometry; tractography; connectivity; motor cortex; posterior parietal cortex; cerebellum; vesicular glutamate transporter;

    Abstract : Traditionally, structural plasticity in the human brain has been considered to follow a linear or asymptotic increase over the course of training. However, recent studies using structural MRI revealed transient increases in grey matter volume (GMV) with learning. READ MORE

  5. 3. Molecular Characterization of Experimental Traumatic Brain Injury

    Author : Charlotte Israelsson; Ted Ebendal; Lars Hillered; Anders Lewén; Henrik Hagberg; Uppsala universitet; []
    Keywords : Neurosciences; traumatic brain injury; transcripts; GeneChip; chemokine; inflammation; mouse brain; neuroprotection; neuronal injury; neuroregeneration; astrocytosis; Neurovetenskap;

    Abstract : Traumatic brain injury (TBI) is the most common cause of mortality and disability in the younger (.... READ MORE

  6. 4. Modeling glioblastoma heterogeneity to decipher its biology

    Author : Yuan Xie; Lene Uhrbom; Massimo Squatrito; Uppsala universitet; []
    Keywords : MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; Glioblastoma multiforme; biobank; GBM cells; cell of origin; LGR5; OPCs;

    Abstract : Glioblastoma multiforme (GBM) is the most common and lethal form of primary brain tumor that mainly affects adults. GBM displays remarkable intra- and inter-tumoral heterogeneity and contains a subpopulation of cells named glioma stem cells that is believed to be responsible for tumor maintenance, progression and recurrence. READ MORE

  7. 5. Inflammation and neuroprotective strategies in the immature brain after hypoxic-ischemic brain injury

    Author : Pernilla Svedin; Göteborgs universitet; []
    Keywords : hypoxia-ischemia; LPS; immature; brain; inflammation; NAC; melatonin; G-2mPE; MMP-9; MMP-12;

    Abstract : Perinatal brain injury, as a result of hypoxia-ischemia (HI) or infection/HI, is a major cause of acute mortality and neurological morbidity in infants and children. The mechanisms of perinatal HI are not fully understood, which makes it difficult to find effective treatment. READ MORE