Search for dissertations about: "mouse development"

Showing result 1 - 5 of 1046 swedish dissertations containing the words mouse development.

  2. 1. Development of the Mouse Lateral Telencephalon

    Author : Jan Stenman; Institutionen för experimentell medicinsk vetenskap; []
    Keywords : MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; teratologi; embryologi människa ; Utvecklingsbiologi; ontogeny; embryology human ; teratology; Development biology; progenitor domains; striatum; olfactory bulb; amygdala; development; telencephalon; patterning; mouse;

    Abstract : The telencephalon is the most rostral part of the vertebrate central nervous system and is comprised of a number of structures important for voluntary movements and higher cognitive processes. This thesis focuses on the genetic mechanisms that control development of a number of telencephalic structures: the olfactory bulb, the striatum as well as the lateral and basolateral nuclei of the amygdala. READ MORE

  4. 2. Studies of Spinal Motor Control Networks in Genetically Modified Mouse Models

    Author : Henrik Gezelius; Klas Kullander; Ted Ebendal; Martyn Goulding; Uppsala universitet; []
    Keywords : MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; acetyl choline; central nervous system; central pattern generator; Cre recombinase; development; genetic screen; glutamate; interneuron; motor neuron; mouse; mouse genetics; movement; network; neuronal network; nicotinic receptors; physiology; Renshaw cell; rhythm; spinal cord; transmitter; Neuroscience; Neurovetenskap; Neurobiology; Neurobiologi; Molecular neurobiology; Molekylär neurobiologi; Neurophysiology; Neurofysiologi; Neurobiology; Neurobiologi; medicinsk utvecklings- och neurobiologi; Developmental Neurosciences;

    Abstract : Spinal neurons are important in several aspects motor control. For example, the neurons essential for locomotor movements reside in the ventral spinal cord. In this thesis, different motor control functions are being related to neuronal populations defined by their common expression of a gene. READ MORE

  5. 3. Cellular Interactions with Extracellular Matrix During Development and in Muscle Disease

    Author : Carl-Fredrik Tiger; Anders Aspberg; Uppsala universitet; []
    Keywords : NATURVETENSKAP; NATURAL SCIENCES; Cell and molecular biology; integrin; laminin; collagen; muscle; tendon; skeleton; mouse; human; development; Cell- och molekylärbiologi; Cell and molecular biology; Cell- och molekylärbiologi; molekylär cellbiologi; Molecular Cellbiology;

    Abstract : The formation and maintenance of tissues in multicellular animals are crucially dependent on cellular interactions with the extracellular matrix (ECM). Two different studies on such interactions are presented herein. READ MORE

  6. 4. Functions of Heparan Sulfate During Mouse Development : Studies of Mice with Genetically Altered Heparan Sulfate Biosynthesis

    Author : Maria Ringvall; Lena Kjellén; Erik Forsberg; Ulf Lindahl; Erika Gustafsson; Uppsala universitet; []
    Keywords : NATURVETENSKAP; NATURAL SCIENCES; Developmental biology; embryonic development; gene targeting; lung development; ossification; heparan sulfate; heparin; N-deacetylase N-sulfaotransferase; NDST; proteoglycan; morphogen; biosynthesis; Utvecklingsbiologi; Developmental biology; Utvecklingsbiologi;

    Abstract : Heparan sulfate (HS) is a ubiquitous polysaccharide on the cell surface and in the extracellular matrix. HS is an important actor in the regulation of cell signaling, especially in the developing embryo. READ MORE

  7. 5. Heparan Sulfate and Development : A Study of NDST Deficient Mice and Embryonic Stem Cells

    Author : Katarina Holmborn; Lena Kjellén; Erik Forsberg; Catherine L. Merry; Uppsala universitet; []
    Keywords : MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; Cell and molecular biology; heparan sulfate; proteoglycan; biosynthesis; N-deacetylase N-sulfotransferase; NDST; gene targeting; embryonic development; lung development; mast cells; Cell- och molekylärbiologi;

    Abstract : Heparan sulfate (HS) proteoglycans consist of sulfated HS chains covalently bound to core proteins. They are ubiquitously expressed, on the cell surface and in the extracellular matrix, throughout the body. READ MORE