Search for dissertations about: "mouse embryonic fibroblasts"

Showing result 1 - 5 of 27 swedish dissertations containing the words mouse embryonic fibroblasts.

2. 1. Plant Calreticulins -Calcium-binding proteins with many functions

   Author : Anna Christensen; Biokemi och Strukturbiologi; []
   Keywords : NATURVETENSKAP; NATURAL SCIENCES; tobacco; plant; calreticulin; isoforms; Arabidopsis; localization; mouse embryonic fibroblasts;

   Abstract : Endoplasmic reticulum (ER) plays an important role in protein synthesis, folding, maturation and transport of newly synthesized proteins, as well as the regulation of cellular Ca2+ homeostasis. A protein that is involved in several of these functions in the ER is calreticulin (CRT), which is a Ca2+-binding chaperone that resides in the lumen of the ER. READ MORE

4. 2. Functions of platelet-derived growth factor-A during organogenesis

   Author : Linda Karlsson; Göteborgs universitet; []
   Keywords : MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; platelet-derived growth factor-A; knockout; mouse organogenesis; epithelial-mesenchymalinteractions; skin; hair follicles; CNS; lung; gastrointestinal villus;

   Abstract : The formation of organs during embryonic development is calledorganogenesis. This process is regulated by the genes residing in the genome. READ MORE

5. 3. Optimisation of human embryonic stem cell derivation and culture : towards clinical quality

   Author : Susanne Ström; Karolinska Institutet; Karolinska Institutet; []
   Keywords : hESC;

   Abstract : For clinical grade human embryonic stem cell (hESC) lines, a robust derivation and culture system without any substances having animal origin would be optimal. The general aims of these studies have been to gradually improve our hESC derivation and cultures. READ MORE

6. 4. Focus on fibroblasts : development, plasticity, and therapeutic challenges in the cardiac fibroblast lineage

   Author : Giorgia Palano; Karolinska Institutet; Karolinska Institutet; []
   Keywords : ;

   Abstract : Cardiac fibroblasts (CFs) are cells of mesenchymal origin and represent a heterogeneous population in the mammalian heart. They secrete extracellular matrix (ECM) molecules providing structural support during heart development and homeostasis. In response to injury, CFs are activated and undergo phenotypic conversion to myofibroblasts (myoFBs). READ MORE

7. 5. Healing of tympanic membrane perforations : an experimental study

   Author : Anisur Rahman; Karolinska Institutet; Karolinska Institutet; []
   Keywords : Embryonic stem cells; Healing; Immunosuppressive; Laser; Mesenchymal stem cells; Moiré interferometry; Myringotomy; Perforation; Tympanic membrane;

   Abstract : Most acute tympanic membrane perforations heal spontaneously without any residual complication, whereas a fraction transforms into a chronic perforation. The current treatment of a chronic perforation is surgical repair, which is a costly, time consuming and uncomfortable procedure particularly for the pediatric patients. READ MORE