Search for dissertations about: "mouse olfactory system"
Showing result 1 - 5 of 22 swedish dissertations containing the words mouse olfactory system.
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1. Olfactory Transfer of Analgesic Drugs After Nasal Administration
Abstract : Nasal administration of analgesics for achieving rapid pain relief is currently a topic of great interest. The blood-brain barrier (BBB) restricts access to the central nervous system (CNS) for several central-acting drugs, such as morphine and dihydroergotamine, which results in a substantial effect delay. READ MORE
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2. Zonal organization of the mouse olfactory systems
Abstract : Animals survey their environment for relevant odorous chemical compounds by means of the olfactory system. This system is in most vertebrates divided into a main and accessory olfactory system with two specialized neuroepithelia, the olfactory and the vomeronasal epithelium, respectively. READ MORE
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3. Development of the Mouse Lateral Telencephalon
Abstract : The telencephalon is the most rostral part of the vertebrate central nervous system and is comprised of a number of structures important for voluntary movements and higher cognitive processes. This thesis focuses on the genetic mechanisms that control development of a number of telencephalic structures: the olfactory bulb, the striatum as well as the lateral and basolateral nuclei of the amygdala. READ MORE
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4. Models for the Transfer of Drugs from the Nasal Cavity to the Central Nervous System
Abstract : The blood-brain barrier restricts the access of many compounds, including therapeutic agents, to the brain. Several human studies indicate that nasal administration of hydrophilic compounds, such as peptides, can bypass the blood-brain barrier. The aims of this thesis were to develop and refine models for this direct nose-to-brain transfer. READ MORE
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5. Effects of retinoic acid in the mouse olfactory sensory systems
Abstract : A common characteristic in neurodegenerative diseases of the brain is death of specific neuronal populations. The lack of neuron proliferation and axon extension in most parts of the central nervous system leads to chronic loss of neurons in the case of injury or disease. READ MORE