Search for dissertations about: "mouse"
Showing result 16 - 20 of 2226 swedish dissertations containing the word mouse.
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16. Molecular characterization of prostate hyperplasia in prolactin transgenic mice
Abstract : Benign prostatic hyperplasia (BPH) and prostate cancer are age-related diseases, affecting a majority of elderly men in the western world, and are known to be influenced by several different hormones, including sex hormones. Although the hormone prolactin (PRL) is well known to exert trophic effects on prostate cells, its involvement in the pathophysiology is still poorly characterized. READ MORE
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17. The roles of the plasminogen activator and matrix metalloproteinase systems in ovulation and corpus luteum formation
Abstract : Proteases of the plasminogen activator (PA) and the matrix metalloproteinase (MMP) enzyme systems are expressed in the ovulatory follicle and in the developing corpus luteum (CL). However, the functional role of these extracellular degrading protease systems in the ovulatory and CL development processes remains elusive. READ MORE
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18. On ischemia/reperfusion injury and rejection in concordant xenotransplantation to the rat
Abstract : Studies in concordant (without preformed antibodies) rodent xenotransplantation (transplantation between species) models have focused, to date, on immunological disparities. In allotransplantation (transplantation within species), there is evidence suggesting that early ischemic events may contribute to later rejection episodes and to the development of chronicrejection features. READ MORE
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19. Targeting apoptosis-inducing factor as a novel therapeutic strategy for preventing perinatal brain injury
Abstract : Perinatal complications such as asphyxia can cause brain injuries that are often associated with subsequent neurological deficits. The mechanisms of perinatal brain injury are not fully understood, but mitochondria play a prominent role, not only due to their central function in metabolism, but also because many proteins with apoptosisrelated functions are located in the mitochondrion. READ MORE
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20. Neogenesis and alloxan toxicity in pancreatic islets, with special reference to the transplanted human β-cell
Abstract : The aim of this work was to study whether adult human pancreatic β-cells have the capacity to proliferate in culture and after transplantation to the renal subcapsular space of mice. An immunosuppressive regimen for human islet discordant xenotransplantation to mice was designed. READ MORE