Search for dissertations about: "mtDNA"

Showing result 1 - 5 of 95 swedish dissertations containing the word mtDNA.

  1. 1. Crisis in Energy Metabolism - Mitochondrial Defects and a New Disease Entity

    Author : Gittan Kollberg; Göteborgs universitet.; Gothenburg University.; [2006]
    Keywords : MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; Energy metabolism; Mitochondrial Disorders; mtDNA; multiple mtDNA deletions; Alpers-Huttenlocher syndrome; POLG1; GYS1; glycogen synthase; point mutation; Polymerase gamma;

    Abstract : Impairment of energy metabolism may be associated with severe implications for affected individuals since all fundamental cell functions are energy-dependent. Disorders of energy metabolism are often genetic and associated with defects in the oxidative phosphorylation in mitochondria. READ MORE

  2. 2. Analysis of the origin and spread of the domestic dog using Y-chromosome DNA and mtDNA sequence data

    University dissertation from Stockholm : KTH Royal Institute of Technology

    Author : Mattias Oskarsson; KTH.; [2012]
    Keywords : TEKNIK OCH TEKNOLOGIER; ENGINEERING AND TECHNOLOGY; mtDNA; domestication; Y-chromosome; SNP; ASY; dog; dingo;

    Abstract : The domestic dog was probably the first domesticated animal, and the only one to spread to all continents in ancient times. The dog is one of the most phenotypically diverse animals, a result of human selection throughout dog history. READ MORE

  3. 3. Analysis of domestic dog mitochondrial DNA sequence variation for forensic investigations

    University dissertation from Stockholm : KTH

    Author : Helen Angleby; KTH.; [2005]
    Keywords : TEKNIK OCH TEKNOLOGIER; ENGINEERING AND TECHNOLOGY; Biotechnology; forensics; mtDNA; control region; hair; domestic dog; breed; Bioteknik; TECHNOLOGY Bioengineering; TEKNIKVETENSKAP Bioteknik;

    Abstract : The first method for DNA analysis in forensics was presented in 1985. Since then, the introduction of the polymerase chain reaction (PCR) has rendered possible the analysis of small amounts of DNA and automated sequencing and fragment analysis techniques have facilitated the analyses. READ MORE

  4. 4. Initiation of Mammalian Mitochondrial DNA Replication

    University dissertation from Stockholm : KTH

    Author : Elisabeth Jemt; Göteborgs universitet.; Gothenburg University.; [2014]
    Keywords : NATURVETENSKAP; NATURAL SCIENCES; mitochondria; mtDNA; DNA replication;

    Abstract : Mitochondria produce most of the adenosine triphosphate required in a eukaryotic cell and they contain their own genome. The mitochondrial DNA (mtDNA) is a double stranded circular molecule that codes for proteins required for cellular respiration and RNA molecules involved in translation of these proteins. READ MORE

  5. 5. Inflammatogenic properties of endogenous DNA

    University dissertation from Stockholm : KTH

    Author : Shahin Hajizadeh; Göteborgs universitet.; Gothenburg University.; [2004]
    Keywords : MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; Inflammation; mtDNA; oxidized DNA; SF; CSF; RA; dementia;

    Abstract : Bacterial DNA and CpG-containing oligodeoxynucleotides (ODNs) induce host inflammatory responses as a result of their content of unmethylated ¡§CpG motifs¡¨. Since the CpG motifs in the mitochondrial (mt) genome are in this respect similar to bacterial DNA, in that they are non-methylated, we investigated whether mtDNA also displays inflammatogenic potential. READ MORE