Search for dissertations about: "mtDNA"
Showing result 1 - 5 of 95 swedish dissertations containing the word mtDNA.
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1. Crisis in Energy Metabolism - Mitochondrial Defects and a New Disease Entity
Abstract : Impairment of energy metabolism may be associated with severe implications for affected individuals since all fundamental cell functions are energy-dependent. Disorders of energy metabolism are often genetic and associated with defects in the oxidative phosphorylation in mitochondria. READ MORE
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2. Analysis of the origin and spread of the domestic dog using Y-chromosome DNA and mtDNA sequence data
University dissertation from Stockholm : KTH Royal Institute of TechnologyAbstract : The domestic dog was probably the first domesticated animal, and the only one to spread to all continents in ancient times. The dog is one of the most phenotypically diverse animals, a result of human selection throughout dog history. READ MORE
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3. Analysis of domestic dog mitochondrial DNA sequence variation for forensic investigations
University dissertation from Stockholm : KTHAbstract : The first method for DNA analysis in forensics was presented in 1985. Since then, the introduction of the polymerase chain reaction (PCR) has rendered possible the analysis of small amounts of DNA and automated sequencing and fragment analysis techniques have facilitated the analyses. READ MORE
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4. Initiation of Mammalian Mitochondrial DNA Replication
University dissertation from Stockholm : KTHAbstract : Mitochondria produce most of the adenosine triphosphate required in a eukaryotic cell and they contain their own genome. The mitochondrial DNA (mtDNA) is a double stranded circular molecule that codes for proteins required for cellular respiration and RNA molecules involved in translation of these proteins. READ MORE
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5. Inflammatogenic properties of endogenous DNA
University dissertation from Stockholm : KTHAbstract : Bacterial DNA and CpG-containing oligodeoxynucleotides (ODNs) induce host inflammatory responses as a result of their content of unmethylated ¡§CpG motifs¡¨. Since the CpG motifs in the mitochondrial (mt) genome are in this respect similar to bacterial DNA, in that they are non-methylated, we investigated whether mtDNA also displays inflammatogenic potential. READ MORE
