Search for dissertations about: "mucin"

Showing result 1 - 5 of 95 swedish dissertations containing the word mucin.

  1. 1. Mucus and mucins during gastrointestinal infections

    Author : Nazanin Navabi; Göteborgs universitet; Göteborgs universitet; Gothenburg University; []
    Keywords : MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; mucin; gastrointestinal cell lines; mucus layer; secreted mucin; cell surface mucin; H. pylori; C. rodentium; ETEC; mucin secretion; goblet cells;

    Abstract : The gastrointestinal tract is protected by a continuously secreted mucus layer formed by mucin glycoproteins. The mucus layer and mucins change dynamically during infection. The main focus of this thesis was to investigate the changes in mucin and the mucus layer in the gastrointestinal tract during infection with the gastrointestinal pathogens C. READ MORE

  2. 2. On the Development of Mucin-based Biomaterial Coatings

    Author : Tomas Sandberg; Karin Caldwell; Jan Carlsson; Thomas Arnebrant; Uppsala universitet; []
    Keywords : MEDICAL AND HEALTH SCIENCES; MEDICIN OCH HÄLSOVETENSKAP; MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; Mucin; Biomaterial; Surface-exposed protein; XPS; Neutrophil; Cell morphology; SEM; QCM-D; Viscoelasticity; Protein-stabilization; HNL; Coating; MG1; BSM; PGM; SEC-MALS-RI; Mucin quantification; Protein adsorption; Ellipsometry; Biomaterials; Biomaterial;

    Abstract : Owing to their key role in mucosal functioning as surface barriers with biospecific interaction potentials, the mucins are interesting candidates for use as surface modifiers in biomaterials applications. In this work, “mild” fractionation procedures were used to prepare mucins of bovine (BSM), porcine (PGM), and human (MG1) origin. READ MORE

  3. 3. Investigating mucin interactions with diverse surfaces for biomedical applications

    Author : Georgia Petrou; Thomas Crouzier; Anette Larsson; KTH; []
    Keywords : MEDICAL AND HEALTH SCIENCES; MEDICIN OCH HÄLSOVETENSKAP; MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; mucus; mucin; protein adsorption; biomaterials; lubrication; mucoadhesion; 4RepCT; Biotechnology; Bioteknologi;

    Abstract : Mucous membranes are covered with mucus, a viscoelastic hydrogel that plays an essential role in their protection from shear and pathogens. The viscoelasticity of mucus is owing to mucins, a group of densely glycosylated proteins. READ MORE

  4. 4. Tumor biological aspects of the mucin-like glycoprotein CD43

    Author : Sirle Laos; Göteborgs universitet; Göteborgs universitet; Gothenburg University; []
    Keywords : ; CD43; leukosialin; sialophorin; mucin; colon adenoma; proteolytic processing; NF-kappaB; p65; chemokine; p53; ARF; Fas; apoptosis; transformation;

    Abstract : Cancer cells overexpress aberrant forms and amounts of mucins, which contribute to tumor development by regulating cell growth, survival, adhesion, invasion and immune responses. CD43, a type I transmembrane protein, is a mucin-like molecule expressed under normal physiological conditions by most hematopoietic cell types. READ MORE

  5. 5. Effect of hydration on thermodynamic, rheological and structural properties of mucin

    Author : Yana Znamenskaya; Malmö högskola; []
    Keywords : mucous gel; mucus; mucin; PGM; BSM; BSM chitosan multilayers; hydration; water sorption isotherm; relative humidity; water activity; bound water; enthalpy of hydration of biopolymer; glass transition; rheology; phase diagram; fiber-like structure; dumbbell-like structure; sorption calorimetry; DSC; QCM-D; SAXS; AFM;

    Abstract : Mucus, an adherent hydrated layer covering the epithelium, is found in all internal tracts of the body and plays an important role in animal and human life. One of the essential functions of mucus is protection of tissues against dehydration. READ MORE