Search for dissertations about: "mucins"

Showing result 16 - 20 of 43 swedish dissertations containing the word mucins.

  2. 16. Aiway Mucins: experimental models for studies of secretions

    Author : Naila Svitacheva; Institutionen för experimentell medicinsk vetenskap; []
    Keywords : MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; cystic fibrosis; bovine trachea; radiolabelling; cell line; primary cell culture; organ culture; mucus; mucin; Endocrinology; secreting systems; diabetology; Endokrinologi; sekretion; diabetologi;

    Abstract : Mucins are essential components of the mucosal barrier. The complexity of the airway mucosal barrier is reflected in the lack of specific treatments to block mucin hypersecretion associated with several respiratory diseases such as chronic bronchitis, asthma and cystic fibrosis. READ MORE

  4. 17. Interactions of Mucins with Biopolymers and Drug Delivery Particles

    Author : Olof Svensson; Malmö högskola; []
    Keywords : NATURVETENSKAP; NATURAL SCIENCES; mucin; chitosan; lactoperoxidase; multilayer; mucoadhesion; nanoparticles; ellipsometry;

    Abstract : The main components in the mucous gels apart from water are mucins, which are proteins with high molecular weights and an abundance of negatively charged oligosaccharide side chains. The aim of the investigations was to characterize interactions between mucins and other proteins that are present in the mucous gel, and also between mucins and components used in pharmaceutical formulations. READ MORE

  5. 18. Evolution of Transmembrane and Gel-forming Mucins Studied with Bioinformatic Methods

    Author : Tiange Lang; Göteborgs universitet; []
    Keywords : ;

    Abstract : All mucosal membranes of the body are covered by mucus, largely made up of the family of large glycoproteins called mucins. These are instrumental for the protection of the underlying epithelia and involved in the pathogenesis of many diseases in the lungs and the intestine. READ MORE

  6. 19. Helicobacter pylori binding to gastric mucins and host glycosylation changes after inoculation

    Author : Sara Lindén; Institutionen för experimentell medicinsk vetenskap; []
    Keywords : MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; Biomedicinska vetenskaper allmänt ; General biomedical sciences; host-parasite interactions; H. pylori adhesin; mucin; Lewis antigen;

    Abstract : Helicobacter pylori may cause gastritis, gastric/duodenal ulcer and gastric cancer. During infection, most H. pylori are found in the gastric mucus layer, but some are attached to, or have penetrated, epithelial cells. The aim of this study is to characterize the binding of H. READ MORE

  7. 20. Helicobacter spp. interactions with mucins: adhesion and mucin regulation of pathogen proliferation and gene expression

    Author : Emma C Skoog; Göteborgs universitet; []
    Keywords : MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; Helicobacter; mucin; glycosylation; Lactobacillus; adhesion; proliferation; gene expression; CagA; SabA; BabA; ArsS; Fur;

    Abstract : Helicobacter pylori colonizes the gastric mucosa of approximately half of the world’s population and is a risk factor for gastritis, peptic ulcers and gastric cancer. H. pylori is surrounded by, and adheres to, the heavily glycosylated mucins that build up the mucus layer. The carbohydrate structures on the mucins that act as ligands for H. READ MORE