Search for dissertations about: "mucosal blood flow"

Showing result 1 - 5 of 32 swedish dissertations containing the words mucosal blood flow.

  2. 1. Gastrointestinal mucosal protective mechanisms : Mudolatory effects of Heliobacter pyroli on the gastric mucus gel barrier and mucosal blood flow in vivo

    Author : Christer Atuma; Uppsala universitet; []
    Keywords : MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; Physiology and anatomy; mucus gel layer; mucosal blood flow; mucus thickness; chronic infection; rat; platelet activating factor; mast cell; nitric oxide; nitric oxide synthase; ketotifen; intra-vital microscopy; microelectrode; laser-Doppler flowmetry; L-NNA; Fysiologi och anatomi; Physiology and pharmacology; Fysiologi och farmakologi; Physiology; fysiologi;

    Abstract : The gastrointestinal mucus gel layer and blood flow are two important mechanisms for protection at the pre-epithelial and sub-epithelial levels, respectively. Helicobacter pylori might circumvent these mechanisms and elicit a chronic inflammatory response with consequent ulcers in the stomach and duodenum. READ MORE

  4. 2. Nitrate, Nitrite and Nitric Oxide in Gastric Mucosal Defense

    Author : Joel Petersson; Lena Holm; Jon Lundberg; Mia Phillipson; Matthew Grisham; Uppsala universitet; []
    Keywords : MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; dietary nitrate; mucus gel layer; mucosal blood flow; mucus thickness; laser-Doppler flowmetry; mucosal damage; intra-vital microscopy; mucosal permeability; Physiology; Fysiologi;

    Abstract : The human stomach normally contains high levels of bioactive nitric oxide (NO). This NO derives from salivary nitrate (NO3-) that is converted to nitrite (NO2-) by oral bacteria and thereafter non-enzymatically reduced in the acidic gastric lumen to NO. READ MORE

  5. 3. Aspects on luminal nitric oxide in relation to oesophageal acid exposure and mucosal integrity

    Author : Mogens Bove; Göteborgs universitet; []
    Keywords : nitric oxide; nitric oxide synthase; acid; gastro-esophageal reflux disease; membrane potentials; saliva; nitrate; blood flow; ferret; histopathology;

    Abstract : Nitric oxide (NO) exerts important neuromuscular control of the oesophagus, but little is known about the sources and effects of the NO present in the distal oesophageal lumen. These questions were presently addressed in both human and animal experiments. READ MORE

  6. 4. Microcirculation, Mucus and Microbiota in Inflammatory Bowel Disease

    Author : Olof Schreiber; Lena Holm; Mia Phillipson; Henrik Sjövall; Uppsala universitet; []
    Keywords : MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; inflammatory bowel diseases; experimental colitis; DSS; TNBS; colonic mucosal blood flow; laser-doppler flowmetry; colonic mucus thickness; MUC2; colonic mucosal barrier function; iNOS; eNOS; probiotics; Lactobacilli; Lactobacillus reuteri; colonic microbiota; T-RFLP; bacterial translocation; intravital microscopy; P-selectin; leukocyte recruitment; platelet recruitment; Physiology; Fysiologi; Physiology; Fysiologi;

    Abstract : Inflammatory bowel diseases, (IBD), are a group of chronic disorders of the gastro-intestinal tract, and include Crohn’s disease (CD) and Ulcerative Colitis (UC). The pathogenesis is not known, but involves at least in part a loss of tolerance towards the commensal colonic microbiota. READ MORE

  7. 5. Helicobacter pylori and Gastric Protection Mechanisms : An in vivo Study in Mice and Rats

    Author : Johanna Henriksnäs; Lena Holm; Lars Engstrand; Erik Persson; Lars Fändriks; Uppsala universitet; []
    Keywords : MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; Physiology; mucus gel layer; mucosal blood flow; mucus thickness; intra-vital microscopy; laser-Doppler flowmetry; pH-sensitive microelectrode; nitric oxide; Helicobacter pylori; bicarbonate secretion; mouse model; Fysiologi; Physiology; Fysiologi;

    Abstract : The stomach is frequently exposed to hazardous agents and to resist this harsh environment, several protective mechanisms exist. Of special interest is the gastric pathogen Helicobacter pylori which causes gastritis, ulcers and cancer but the mechanism leading to these diseases are still unclear. However it is very likely that H. READ MORE