Search for dissertations about: "mucosal permeability"

Showing result 16 - 20 of 46 swedish dissertations containing the words mucosal permeability.

  2. 16. Design of solid dosage forms for mucosal vaccination - Investigations on the influence of excipients on product performance

    Author : Annika Borde; Chalmers tekniska högskola; []
    Keywords : TEKNIK OCH TEKNOLOGIER; ENGINEERING AND TECHNOLOGY; NATURVETENSKAP; NATURAL SCIENCES; MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; TEKNIK OCH TEKNOLOGIER; ENGINEERING AND TECHNOLOGY; hydrophilic matrix tablets; osmotic pressure; protein release; freeze-drying; Vibrio cholerae; mucoadhesion; Bradford Assay; sublingual vaccine tablet; mucosal vaccination;

    Abstract : Most vaccines today are liquid formulations for parental administration. However, there are several drawbacks connected to these vaccines. Since injectable vaccines only induce systemic antibody responses, they are not effective against the various pathogens that affect mucosal surfaces with poor permeability for serum-derived antibodies, e.g. READ MORE

  4. 17. Gastric gland luminal pressure and mucosal protection : An in vivo study in the anesthetized rat

    Author : Ingrid Synnerstad; Uppsala universitet; []
    Keywords : MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; Physiology and anatomy; acid secretion; bicarbonate; epithelial cell surface pH; gastric gland; muscularismucosa; micropuncture; mucosal blood flow; mucus gel thickness; omeprazole; permeability; prostaglandins; ranitidine; rat; Fysiologi och anatomi; Physiology and pharmacology; Fysiologi och farmakologi; Physiology; fysiologi;

    Abstract : The driving force for creation of channels in gastric mucus, for acid and pepsin transport, ismost probably the hydrostatic pressure generated within the gastric gland lumen. The aim ofthis study was to investigate the origin and regulation of the glandular pressure. READ MORE

  5. 18. Influence of Lactic Acid Fermentation on Enteropathogenic Bacteria. Growth Inhibition in Cereal Gruels and in Human Intestine

    Author : Rose Kingamkono; Chalmers tekniska högskola; []
    Keywords : NATURVETENSKAP; NATURAL SCIENCES; intestinal mucosal permeability; enteropathogenic bacteria; enterotoxins; lactic acid fermentation;

    Abstract : Togwa, a lactic-fermented cereal gruel, is widely consumed in Tanzania as a soft drink or used as a complementary food for young children. Studies were conducted to evaluate the potential of togwa to inhibit growth of common enteropathogenic bacteria and heat-labile (LT) enterotoxin production. READ MORE

  6. 19. Gut Mucosal Reactivity to Gluten and Cow´s Milk Protein in Rheumatic Diseases

    Author : Maria Lidén; Roger Hällgren; Gudjón Kristjánsson; Sigrídur Valtýsdóttir; Thomas Skogh; Uppsala universitet; []
    Keywords : MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; Primary Sjögren’s syndrome; rheumatoid arthritis; spondyloarthropathies; rectal challenge; food sensitivity; myeloperoxidase; nitric oxide and barrier permeability; Rheumatology; Reumatologi; Medicine; medicin;

    Abstract : This thesis comprised patients with chronic rheumatic diseases. The studies aimed to elucidate food sensitivity by measuring mucosal inflammatory reactivity and thereby a possible link between the gut and joints. READ MORE

  7. 20. Experimental studies of small intestinal permeability and function in uremia

    Author : Martin Magnusson; Anders Alvestrand; Linköpings universitet; []
    Keywords : MEDICINE; MEDICIN;

    Abstract : The intestinal permeability has been investigated in experimental chronic and acute uremia in rats. The permeability and the mucosal ability to exclude larger molecules have been measured using differently sized polyethylene glycols (PEG 400 and 1000: mean weights of 400 and 1000 dalton, range 326-1162 dalton). READ MORE