Search for dissertations about: "mucosal vaccination"

Showing result 11 - 15 of 33 swedish dissertations containing the words mucosal vaccination.

  2. 11. Mucosal Immunity in Mycobacterial infections

    Author : Anna Tjärnlund; Marita Troye-Blomberg; Andrzej Pawlowski; Anders Örn; Stockholms universitet; []
    Keywords : NATURVETENSKAP; NATURAL SCIENCES; Immunology; Immunologi; immunologi; Immunology;

    Abstract : More than a century after the identification of the tubercle bacillus and the first attempts at vaccination, tuberculosis (TB) still remains one of the world’s most serious infectious diseases. TB, caused by the bacterium Mycobacterium tuberculosis, is typically a disease of the lung, which serves both as port of entry and as the major site of disease manifestation. READ MORE

  4. 12. Genetic vaccination against acute viral disease

    Author : Marina N Fleeton; Karolinska Institutet; Karolinska Institutet; []
    Keywords : Semliki Forest virus; Alphavirus. Influenza A virus; DNA vaccines. Influenza vaccine. Respiratory Syncytial Viruses; Louping Ill. Flavivirus Infections;

    Abstract : This thesis describes the development of recombinant vaccines based on the Semliki Forest virus (SFV) expression system. Immunisation of mice with recombinant virus particles, a layered DNA/RNA plasmid vector, and recombinant self-replicating RNA were carried out and the protective effect of these recombinant vaccines against viral challenge were examined. READ MORE

  5. 13. Genetic modification of cholera toxin B subunit for mucosal anti-infectious or anti-pathologic vaccination

    Author : Hamid Sadeghi; Göteborgs universitet; []
    Keywords : Genetic fusion protein; cholera toxin B subunit; insulin; GST; Oral tolerance;

    Abstract : The development of mucosal vaccines requires antigen delivery systems that can efficiently help to present vaccine antigens to the mucosal immune system. En efficient and well known antigen carrier/delivery system is the B subunit of cholera toxin (CTB). READ MORE

  6. 14. The mucosal immune response against Helicobacter pylori infection

    Author : Sicheng Wen; Karolinska Institutet; Karolinska Institutet; []
    Keywords : ;

    Abstract : H. pylori infection affects more than half of the world’s population. The clinical consequences range from asymptomatic gastritis to peptic ulceration and gastric malignancy. H. READ MORE

  7. 15. Regulation of gut IgA induction by helper T cells

    Author : Inta Gribonika; Göteborgs universitet; []
    Keywords : MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; mucosal immunology; secretory IgA; T regulatory cells; T follicular helper cells; Th17 cells; Peyer s patches; IgA class-switch recombination; germinal centers;

    Abstract : The gut is the largest lymphoid organ in the body. Due to intense and constant exposure to the outside world, it also functions as the most important portal of entry for many pathogens. READ MORE